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personalized medicine

Functional neurological disorders
Gut microbiota and myelination: Crosstalk across the lifespan and microbiota-based modulation strategies

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Gut Microbiota’s Role in Myelination The gut microbiota, a complex community of microorganisms residing in …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging plays a crucial role in understanding Wilson’s disease, a …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging findings in Wilson’s disease reveal significant alterations in brain …

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Functional neurological disorders
Integrated in silico identification of cholinesterase inhibitors from Nyctanthes arbor-tristis

by myneuronews July 23, 2025

by myneuronews July 23, 2025

In silico Screening Methodology The methodology employed in this study integrates advanced computational techniques to …

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Functional neurological disorders
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Integrated Transcriptomic Insights Recent advancements in transcriptomic analysis have opened new avenues for understanding the …

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Functional neurological disorders
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Frmpd3 Function in Epilepsy The study of the Frmpd3 protein reveals its significant role in …

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Functional neurological disorders
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Integrated Transcriptomic Findings The study employs an integrated transcriptomic approach, utilizing high-throughput RNA sequencing to …

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Traumatic brain injury
Get Your Brain in the Game: Using Machine Learning to Predict Recovery Timelines Following Sports-Related Concussion

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Study Overview The research conducted aimed to investigate how machine learning can be utilized to …

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Dementia
Embracing the Modern Biochemistry of Brain Metabolism

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Understanding Brain Metabolism The brain is an extraordinarily energy-demanding organ, consuming approximately 20% of the …

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Functional neurological disorders
Predicting Mental and Neurological Illnesses Based on Cerebellar Normative Features

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Cerebellar Features and Their Role in Mental Illness The cerebellum, traditionally associated with coordination and …

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Spontaneous Regression of Cranial Vault Lymphoma: A Case Report
Case Presentation A 54-year-old male patient, previously healthy with no notable medical history, presented with…
Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis
Study Overview The research aimed to investigate the role of TDP-43 accumulation in the progression…
Reframing Functional Neurological Disorders in Modern Medicine
Reframing the Understanding of FND Functional Neurological Disorder (FND) represents a complex interplay of neurological…
Inpatient cognitive analytic therapy for functional neurological disorder: A mixed methods four-phase single-case experimental design
Study Summary This study focused on evaluating the effectiveness of inpatient cognitive analytic therapy (CAT)…
Outcomes of specialist physiotherapy for functional motor disorder: the Physio4FMD RCT
Study Summary The Physio4FMD randomized controlled trial aimed to evaluate the effectiveness of specialist physiotherapy…

Youth Ages 4 to 13 Trends of Sports Concussions With Loss of Consciousness From 2014-2023 National Electronic Injury Surveillance System
CONCLUSION: The results of this study show a decrease in the overall level of LOC incidence in US youth athletes ages 4 to 13 years from 2014 to 2023 across 8 sports. The data delineate from previous studies that show an exponential increase in LOC incidence; however, the underlying reasons are still unclear and warrant […]
Development of the Common Cognitive Complaints after Concussion (C4) questionnaire: a treatment-planning tool for military service members and veterans with mild traumatic brain injury
CONCLUSION: The C4 adequately captured activity-level functional impairments common to mTBI, and clinicians endorsed its utility as a useful tool to personalize treatment targets.
Psychological Transdiagnostic Processes in Mild Traumatic Brain Injury Recovery: A Scoping Review
CONCLUSIONS: Although interest in TPs and mTBI recovery is growing, current investigations are centered on a narrow range of psychological constructs. Broader investigation of TPs known to maintain psychopathology and greater methodological consistency are needed.
Decreased IL-33 in the brain following repetitive mild traumatic brain injury contributes to cognitive impairment by inhibiting microglial phagocytosis
CONCLUSIONS: Dysfunction of the IL-33/ST2 axis following rmTBI leads to cognitive dysfunction via impairing microglial phagocytosis capacity and promoting neuronal damage. IL-33 would be a promising therapeutic target for alleviating neurodegeneration following rmTBI.
Multidisciplinary rehabilitation and follow-up for children hospitalized with traumatic brain injury
PurposeMost children hospitalized with traumatic brain injury (TBI) acquire new impairments that impact function and health-related quality of life. However, there is a lack of standardized, multidisciplinary, longitudinal rehabilitative services for children with TBI.MethodsThis single center, retrospective study evaluated rehabilitative services during acute hospitalization and identified the frequency of unmet needs, defined as new or […]