Tag:

personalized medicine

Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Functional neurological disorders
Clinical and Neuropathological Evaluations of the New Brunswick Neurological Syndrome of Unknown Cause

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Clinical Characteristics of the New Brunswick Neurological Syndrome The New Brunswick Neurological Syndrome (NBNS) has …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to predict the …

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Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Landscape of Parkinson’s Disease in India Parkinson’s Disease (PD) presents a complex interplay of …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to forecast the …

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Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Factors Influencing Parkinson’s Disease Parkinson’s Disease (PD) is a progressive neurodegenerative disorder primarily characterized …

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Functional neurological disorders
Cholinergic degeneration in prodromal and early Parkinson’s: a link to present and future disease states

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Cholinergic System Dysfunction in Parkinson’s The cholinergic system plays a critical role in various brain …

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Functional neurological disorders
Physical-functional alterations in women with chronic migraine

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Understanding chronic migraine in women Chronic migraine is a complex and debilitating neurological condition that …

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Movement Disorders
Diagnosing migraine from genome-wide genotype data: a machine learning analysis

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Study Overview The prevalence of migraine, a debilitating neurological condition characterized by severe headaches often …

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Functional neurological disorders
Neuroplastic changes in patients with functional seizures following neurobehavioral therapy

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Neuroplastic Mechanisms in Functional Seizures Neuroplasticity refers to the brain’s remarkable ability to change and …

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Reviewer Comment on Li et al.: “Systematic review: mental health outcomes in Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy”
Mental Health Outcomes Mental health outcomes in individuals diagnosed with Guillain-Barré syndrome (GBS) and chronic…
Quinine Sulfate for Muscle Cramps in Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind Crossover Trial
Study Overview The study conducted a randomized, double-blind crossover trial to evaluate the effectiveness of…
The Role of Left Atrial Strain in Differentiating Embolic Stroke of Undetermined Source From Other Acute Ischemic Stroke Subtypes Related to Large-Vessel Occlusion
Background and Significance The study of left atrial strain has emerged as a crucial component…
Raising the bar in migraine prevention: Toward freedom and optimal control
Current Approaches to Migraine Prevention Migraine prevention encompasses a variety of methodologies aimed at reducing…
Evaluating the Homogeneity of the PSP-RS Syndrome beyond Core Features
Evaluate the Homogeneity of PSP-RS Syndrome The Progressive Supranuclear Palsy-Richardson Syndrome (PSP-RS) represents a specific…

Somatic Symptom Disorder After Mild Traumatic Brain Injury
CONCLUSIONS: SSD after mTBI is associated with an increased burden of symptoms, comorbidity, and disability. Early identification of at-risk patients appears feasible. SSD may be a useful framework for conceptualizing poor outcome from mTBI in patients with prominent psychological distress and guiding rehabilitation.
The Relationship Between Sex, Fatigue, and Post-Concussion Symptoms Differs Between Those With Mild Traumatic Brain Injury Versus Trauma Control and Healthy Control Participants
CONCLUSIONS: This study indicates that the vulnerability of females to report elevated PCS in the post-acute period after traumatic injury is specific to those who have incurred a concomitant mTBI. Further, only some subcomponents of fatigue independently explain variance in PCS reporting, with the groups showing variability in these associations. Further work is needed to […]
Patient-Reported Outcomes Measurement Information System (PROMIS) outcomes: Higher odds of adverse mental health when physical function is impaired
PurposeBalance and vestibular disorders have a profound impact on quality of life. Anxiety (ANX) and depression (DEP) are common with dizziness, vertigo, or imbalance. It is unclear whether self-reported anxiety or depression depends on perceived physical function for individuals participating in vestibular rehabilitation (VPT). We hypothesized that individuals with worse physical function would be more […]
Predictors of skull fracture and intracerebral pathology after pediatric traumatic brain injury
CONCLUSION: This paper highlights the burden of TBI in infants and toddlers presenting to the emergency department and highlights the differences in presentation of this common complaint. Better understanding of this population will help to form better strategies or to amend current management practices in order to provide more effective treatment to such patients, especially […]
Optimal Diagnostic Strategies for Concussion-Related Vision Disorders: A Review
Concussions are a mild form of traumatic brain injury (TBI) that is typically self-limited and transient with a high prevalence within our communities. Due to the vast visual network interconnectivity, visual symptoms secondary to a concussion occur about 90% of the time. A gold standard to confirm concussion acutely has not been well established. Visual […]