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personalized medicine

Functional neurological disorders
Fully biodegradable dendrimers as novel nanodrugs for amyloid-β-induced neurotoxicity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Biodegradable Dendrimers: A Novel Approach Dendrimers are highly branched molecules that can be customized at …

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Functional neurological disorders
A narrative literature review of white matter microstructure in individuals at clinical high risk for psychosis

by myneuronews May 23, 2025

by myneuronews May 23, 2025

White Matter Microstructure in Psychosis White matter, the tissue in the brain that consists of …

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Traumatic brain injury
Exercise plasma improves traumatic brain injury outcomes in mice

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Exercise-Induced Plasma Effects Physical activity is known to have numerous beneficial effects on health, particularly …

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Functional neurological disorders
Fully biodegradable dendrimers as novel nanodrugs for amyloid-β-induced neurotoxicity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Material and Methods The study on fully biodegradable dendrimers as novel nanodrugs targeting amyloid-β-induced neurotoxicity …

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Functional neurological disorders
A narrative literature review of white matter microstructure in individuals at clinical high risk for psychosis

by myneuronews May 23, 2025

by myneuronews May 23, 2025

White Matter Microstructure and Psychosis Risk White matter microstructure plays a critical role in understanding …

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Headaches
Ergotamine enhances circadian amplitude and diurnally mitigates nitroglycerin-induced mechanical hypersensitivity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Effects of Ergotamine on Circadian Rhythm Recent investigations have illuminated the role of ergotamine in …

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Traumatic brain injury
Cost-effectiveness of Cerebrolysin as an add-on treatment for neurorecovery after traumatic brain injury

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Cerebrolysin in Traumatic Brain Injury Cerebrolysin is a neuropeptide mixture derived from porcine brain tissue, …

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Functional neurological disorders
Aggressive and Refractory Attack of AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder Treated With Ravulizumab: A Case Report

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Clinical Presentation and Diagnosis In this case report, the patient presented with symptoms characteristic of …

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Functional neurological disorders
Convergent mapping of a tremor treatment network

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Mapping the Tremor Treatment Network The recent exploration into the tremor treatment network provides a …

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Functional neurological disorders
HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia

by myneuronews May 20, 2025

by myneuronews May 20, 2025

HSD17B1 Role in Trophoblast Differentiation The study of HSD17B1 (Hydroxysteroid Dehydrogenase Type 1) highlights its …

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Understanding factors influencing the return to physical activity, perspectives of adults with concussion/mild traumatic brain injury: A qualitative study
Understanding the factors that influence the return to physical activity can help to modify behaviour to enhance the recovery of symptoms and physical activity. We conducted 14 semi-structured interviews to explore the barriers and facilitators to returning to physical activity in adults following a mild traumatic brain injury (TBI). The study design was informed by […]
Clinical Utility of the Sport Concussion Office Assessment Tool 6 (SCOAT6) and Other Select Multidomain Assessments for Subacute Sport-Related Concussion
CONCLUSIONS: The PCSI, timed tandem gait, and mVOMS components of the SCOAT6 were useful in identifying sport-related concussion. However, verbal cognitive tests, orthostatic vital signs, and clinical balance components were not useful for this purpose. The CP Screen, additional items from the full version of the VOMS, and ImPACT memory and processing speed were also […]
Persistent Post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies
INTRODUCTION: Persistent post-concussion syndrome (PCS) following mild traumatic brain injury (mTBI) represents a growing global health challenge that significantly impacts patients' quality of life. Despite advances in acute concussion management, there remains a critical need for effective, evidence-based treatments for chronic PCS, as current interventions show limited success in addressing both symptoms and underlying pathophysiology.
Time-limited association between plasma transfusion and mortality in pediatric traumatic brain injury
CONCLUSION: This study reports a significant association between early plasma administration and a lower risk of 4-hour mortality among children with severe TBI that does not persist at or beyond 24 hours. While these data suggest that plasma resuscitation may extend the window for lifesaving intervention, additional prospective data are needed.
Comparing the sensitivity and specificity of novel motor assessments for traumatic brain injury
CONCLUSION: MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.