Two Novel Variants in MT-RNR1 Gene Associated with Hereditary Optic Neuropathy: A Case Report
Study Overview Hereditary optic neuropathy comprises a group of genetic disorders characterized by the degeneration of retinal ganglion cells, leading […]
The Dual Role of Connexins in Stroke, Neurotrauma, Neurodegenerative and Psychiatric Disorders: A Global Systematic Review
Background on Connexins Connexins are a family of integral membrane proteins that form gap junctions, which are specialized intercellular channels
The Role of Cytokines in Traumatic Brain Injury
Impact of Cytokines on Neuroinflammation Cytokines play a pivotal role in the immune response of the central nervous system, particularly
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The gut microbiome in pediatric-onset acquired demyelinating syndromes by myelin oligodendrocyte glycoprotein antibody status
Study overview This research investigates the role of the gut microbiome in pediatric patients who develop acquired demyelinating syndromes (ADS),
Spleen-brain axis regulates myelin integrity via TGF-beta1 signaling in cuprizone-induced demyelination and remyelination model
Spleen-brain axis and myelin integrity The connection between the spleen and brain is a crucial aspect of the immune system’s
T cell-mediated immunodysregulation in multiple sclerosis: from pathogenic subsets to therapeutic advances
Pathogenic Mechanisms The role of T cells in the pathogenesis of multiple sclerosis (MS) has garnered considerable attention in recent
T cell-mediated immunodysregulation in multiple sclerosis: from pathogenic subsets to therapeutic advances
Pathogenic Mechanisms of T Cells in Multiple Sclerosis Multiple sclerosis (MS) is a complex neurodegenerative disease where the immune system
MicroRNA profiles in multiple sclerosis: A review of the literature
MicroRNA Role in Multiple Sclerosis MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a pivotal role in the regulation
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MicroRNA-mRNA Regulatory Network Associated with Cognitive Impairment in Multiple Sclerosis
MicroRNA-MRNA Interaction Dynamics MicroRNAs (miRNAs) are short, non-coding RNA molecules that play a crucial role in gene regulation by interacting
Expanding the Clinical Spectrum of LYRM7-Associated Mitochondrial Complex III Deficiency: Insights from New Cases and Literature Review
Clinical Presentation and Variability The clinical presentation of LYRM7-associated mitochondrial complex III deficiency showcases significant variability among affected individuals, emphasizing