Tag:

personalized medicine

Traumatic brain injury
Optimizing pediatric “Mild” traumatic brain injury assessments: A multi-domain random forest analysis of diagnosis and outcomes

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Overview The research examines the factors influencing the assessment, diagnosis, and outcomes associated with …

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Functional neurological disorders
Predicting Mental and Neurological Illnesses Based on Cerebellar Normative Features

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Cerebellar Features and Their Role in Mental Illness The cerebellum, traditionally associated with coordination and …

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Headaches
Genome-wide associations spanning 194 in-hospital drug dosage change phenotypes highlight diverse genetic backgrounds in concurrent drug therapy

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Overview The research aimed to investigate the genetic factors influencing drug dosage adjustments during …

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Functional neurological disorders
OCNDS core features are conserved across variants, with loop-region mutations driving greater symptom burden

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Core Features of OCNDS OCNDS, or Obsessive-Compulsive and Nervous System Disorders, presents a set of …

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Traumatic brain injury
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer’s disease

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Study Overview The study aimed to explore the genetic underpinnings of Alzheimer’s disease (AD) through …

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Functional neurological disorders
Disordered Ru-O6 Octahedrons for Efficient and Selective Electro-oxidation of Sulfide to Sulfoxide via Boosted Surface Oxygen Kinetics

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Mechanism of Electro-oxidation Electro-oxidation processes are fundamental in transforming chemical compounds, particularly in promoting desirable …

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Functional neurological disorders
A novel cause of type 1 von Willebrand disease: impaired exocytosis of Weibel-Palade bodies due to biallelic MADD variants

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Novel Mechanism of Type 1 Von Willebrand Disease The study uncovers a previously unrecognized mechanism …

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Functional neurological disorders
A novel cause of type 1 von Willebrand disease: impaired exocytosis of Weibel-Palade bodies due to biallelic MADD variants

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Novel Mechanism of Type 1 Von Willebrand Disease Recent research has uncovered a previously unrecognized …

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Headaches
Aggressive Craniospinal Recurrence of a PTEN-Mutated Sinonasal Teratocarcinosarcoma: A Case Report

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Case Presentation A 45-year-old male presented with a persistently obstructed nasal passage and occasional epistaxis …

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Functional neurological disorders
Shared neural signatures in Functional Neurological Disorder and Chronic Pain: a multimodal narrative review

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Neural Mechanisms in FND and Chronic Pain Research into the neural mechanisms underlying Functional Neurological …

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Clinical characteristics and treatment outcomes in patients with Niemann-Pick disease type C (NP-C): a cross-sectional study
Study Overview This research focuses on the clinical characteristics and treatment outcomes of individuals diagnosed…
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia
Study Overview The research presents an extensive analysis aimed at identifying potential biomarkers for frontotemporal…
Functional Neurological Disorder: A Case of Twisted Toes and Dystonia
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) is characterized by neurological symptoms that cannot…
Predictors of Morbidity and Mortality After Fall-related Traumatic Brain Injury
Study Overview The research conducted on predictors of morbidity and mortality following fall-related traumatic brain…
The effects of color and neutral density filters on dynamic accommodation in individuals with mild traumatic brain injury
Study Overview This study examines how color and neutral density filters affect the dynamic accommodation…

Probing Modulation of Attentional Correlates with Aerobic Exercise in Individuals with a History of Concussion
CONCLUSIONS: The findings demonstrated acute exercise improved accuracy among CH individuals, and performance monitoring is impacted negatively long term following a concussion.
Differential Neuroendocrine Responses and Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis Following Repeated Mild Concussive Impacts and Blast Exposures in a Rat Model
Traumatic brain injury (TBI) remains a significant public health concern, particularly among military personnel and contact sport athletes who are frequently exposed to repeated blast overpressure waves and mild concussive impacts, respectively. While moderate and severe TBIs have been extensively studied, the long-term neuroendocrine consequences of mild, repetitive brain trauma are poorly understood. In this […]
Collision Course: A Decade of Traumatic Brain Injury Trends and the Impact of Urban Safety Initiatives in Eastern Massachusetts
Background/Objectives: Traumatic brain injuries (TBI) account for over a third of all injury-related deaths, predominantly due to motor vehicle collisions (MVC). This study provides a comprehensive analysis of TBI trends in Eastern Massachusetts, focusing on injuries resulting from motorcycle MVCs (mMVC), non-motorcycle MVCs (nmMVC), and pedestrian-vehicle strikes (PVS). Methods: A retrospective analysis was conducted on […]
The interaction between neck pain and known determinates of delayed return to play among NCAA student-athletes: a CARE consortium study
CONCLUSIONS: These results suggest that independent of an individual's sex, sport contact level, and/or race, the presence of neck pain following a suspected concussion should be further evaluated and differentially diagnosed to rule out comorbid pathologies that may be contributing to PPCS following a suspected concussion.
Triamcinolone-loaded nanocarriers: a novel strategy to mitigate cognitive and emotional sequelae induced by traumatic brain injury via modulation of oxidative stress
INTRODUCTION: Traumatic brain injury is the leading cause of death and disability in individuals under 40 years old. It induces various neuropathological outcomes, including cognitive, emotional, and physiological deficits, likely linked to early neuroinflammatory processes. In an animal model, mild traumatic brain injury (mTBI) has been shown to elevate oxidative stress biomarkers, such as advanced […]