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personalized medicine

Functional neurological disorders
Will adaptive deep brain stimulation for Parkinson’s disease become a real option soon? A Delphi consensus study

by myneuronews May 5, 2025

by myneuronews May 5, 2025

Adaptive Deep Brain Stimulation Approaches Adaptive deep brain stimulation (aDBS) represents a significant evolution in …

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Functional neurological disorders
Reduced microstructural white matter integrity is associated with the severity of physical symptoms in functional neurological disorder

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Microstructural Changes in White Matter Research indicates that the architecture of brain white matter plays …

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Movement Disorders
Exploring the association between serotonin transporter promoter region methylation levels and depressive symptoms: a systematic review and multi-level meta-analysis

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Background and Rationale The relationship between biological factors, particularly genetic and epigenetic influences, and psychological …

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Functional neurological disorders
Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Clinical Efficacy of Thalamotomy The use of bilateral focused ultrasound thalamotomy (FUS) represents a significant …

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Functional neurological disorders
Personality assessment inventory sex differences in people with epileptic and functional seizures

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Personality Traits in Epileptic Seizures The examination of personality traits among individuals experiencing epileptic seizures …

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Traumatic brain injury
Hybrid membrane-coated Cyclosporine A nanocrystals preventing secondary brain injury via alleviating neuroinflammatory and oxidative stress

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Therapeutic Approach The therapeutic strategy explored in this study focuses on utilizing hybrid membrane-coated nanocrystals …

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Stroke
Proteome-Wide Genetic Study in East Asians and Europeans Identified Multiple Therapeutic Targets for Ischemic Stroke

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Genetic Insights into Ischemic Stroke Ischemic stroke, a condition where blood flow to the brain …

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Functional neurological disorders
Low intensity rTMS in adolescent mice affects visuomotor behaviour with no impact on visual topography

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Effects of Low Intensity rTMS on Visuomotor Behaviour The study examined the effects of low-intensity …

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Functional neurological disorders
Autoimmune psychosis: Psychopathological patterns and outcome after immunotherapy

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Autoimmune Psychosis Overview Autoimmune psychosis is an emerging area of interest in neurology and psychiatry, …

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Traumatic brain injury
Single-Quantum Sodium MRI at 3T for the Separation of Mono- and Bi-T2 Sodium Signals

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Study Overview The study investigates an innovative approach to magnetic resonance imaging (MRI) aimed at …

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Reviewer Comment on Li et al.: “Systematic review: mental health outcomes in Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy”
Mental Health Outcomes Mental health outcomes in individuals diagnosed with Guillain-Barré syndrome (GBS) and chronic…
Quinine Sulfate for Muscle Cramps in Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind Crossover Trial
Study Overview The study conducted a randomized, double-blind crossover trial to evaluate the effectiveness of…
The Role of Left Atrial Strain in Differentiating Embolic Stroke of Undetermined Source From Other Acute Ischemic Stroke Subtypes Related to Large-Vessel Occlusion
Background and Significance The study of left atrial strain has emerged as a crucial component…
Raising the bar in migraine prevention: Toward freedom and optimal control
Current Approaches to Migraine Prevention Migraine prevention encompasses a variety of methodologies aimed at reducing…
Evaluating the Homogeneity of the PSP-RS Syndrome beyond Core Features
Evaluate the Homogeneity of PSP-RS Syndrome The Progressive Supranuclear Palsy-Richardson Syndrome (PSP-RS) represents a specific…

Somatic Symptom Disorder After Mild Traumatic Brain Injury
CONCLUSIONS: SSD after mTBI is associated with an increased burden of symptoms, comorbidity, and disability. Early identification of at-risk patients appears feasible. SSD may be a useful framework for conceptualizing poor outcome from mTBI in patients with prominent psychological distress and guiding rehabilitation.
The Relationship Between Sex, Fatigue, and Post-Concussion Symptoms Differs Between Those With Mild Traumatic Brain Injury Versus Trauma Control and Healthy Control Participants
CONCLUSIONS: This study indicates that the vulnerability of females to report elevated PCS in the post-acute period after traumatic injury is specific to those who have incurred a concomitant mTBI. Further, only some subcomponents of fatigue independently explain variance in PCS reporting, with the groups showing variability in these associations. Further work is needed to […]
Patient-Reported Outcomes Measurement Information System (PROMIS) outcomes: Higher odds of adverse mental health when physical function is impaired
PurposeBalance and vestibular disorders have a profound impact on quality of life. Anxiety (ANX) and depression (DEP) are common with dizziness, vertigo, or imbalance. It is unclear whether self-reported anxiety or depression depends on perceived physical function for individuals participating in vestibular rehabilitation (VPT). We hypothesized that individuals with worse physical function would be more […]
Predictors of skull fracture and intracerebral pathology after pediatric traumatic brain injury
CONCLUSION: This paper highlights the burden of TBI in infants and toddlers presenting to the emergency department and highlights the differences in presentation of this common complaint. Better understanding of this population will help to form better strategies or to amend current management practices in order to provide more effective treatment to such patients, especially […]
Optimal Diagnostic Strategies for Concussion-Related Vision Disorders: A Review
Concussions are a mild form of traumatic brain injury (TBI) that is typically self-limited and transient with a high prevalence within our communities. Due to the vast visual network interconnectivity, visual symptoms secondary to a concussion occur about 90% of the time. A gold standard to confirm concussion acutely has not been well established. Visual […]