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personalized medicine

Traumatic brain injury
Neural Network Classification of Barnes Maze Search Strategy Utilization

by myneuronews July 28, 2025

by myneuronews July 28, 2025

Study Overview This research focuses on the application of neural network techniques to classify the …

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Functional neurological disorders
GSAformer: Group sparse attention transformer for functional brain network analysis

by myneuronews July 27, 2025

by myneuronews July 27, 2025

Methodology Overview The study introduced GSAformer, a novel model designed to improve the analysis of …

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Dementia
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research focuses on the exploration of blood biomarkers that indicate neuronal hyperplasticity, …

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Dementia
Cortical inhibitory and facilitatory alterations in the continuum of alpha-synucleinopathies

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Cortical Inhibition in Alpha-Synucleinopathies Alterations in cortical inhibition have been observed in alpha-synucleinopathies, which include …

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Functional neurological disorders
Gut microbiota and myelination: Crosstalk across the lifespan and microbiota-based modulation strategies

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Gut Microbiota’s Role in Myelination The gut microbiota, a complex community of microorganisms residing in …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging plays a crucial role in understanding Wilson’s disease, a …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging findings in Wilson’s disease reveal significant alterations in brain …

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Functional neurological disorders
Integrated in silico identification of cholinesterase inhibitors from Nyctanthes arbor-tristis

by myneuronews July 23, 2025

by myneuronews July 23, 2025

In silico Screening Methodology The methodology employed in this study integrates advanced computational techniques to …

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Functional neurological disorders
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Integrated Transcriptomic Insights Recent advancements in transcriptomic analysis have opened new avenues for understanding the …

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Functional neurological disorders
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Frmpd3 Function in Epilepsy The study of the Frmpd3 protein reveals its significant role in …

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A sensor-based gait measure for identifying invalid performance in simulated mTBI: an experimental proof of concept
CONCLUSIONS: Findings offer preliminary support for the ability of an automated gait-based measure to capture invalid performance and inform investigations regarding effort. These experimental findings represent a first step in exploring the potential clinical utility of the BKG as a measure of performance validity.
The clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury (STOP-D): study protocol for a multi-centre randomised controlled trial
BACKGROUND: Traumatic brain injury (TBI) is a common presentation in emergency departments worldwide. Approximately 1.4 million adults present with TBI in England and Wales annually. Post-TBI depression (PTD) is a common neuropsychiatric consequence, affecting up to 50% of patients within two years, and is associated with adverse functional outcomes. PTD remains underdiagnosed and undertreated. Sertraline, […]
The Relationship of Prior Concussion and Contact Sport Exposure With Cortical Macro and Microstructure
Changes in cortical gray matter are a key feature of neurodegenerative diseases that have been linked with concussion and repetitive head impacts (RHIs). Prior evidence implicates prior concussion and RHI in reduced cortical thickness or volume in temporal and frontal regions, with results largely restricted to older retired contact sport athletes. Fewer studies have investigated […]
Impact of Modified Brain Injury Guideline Incorporating Neurosurgical Consultation on Resource Utilization and Follow-Up Care in Complicated Mild Traumatic Brain Injury
CONCLUSION: Implementation of a resource utilization-focused protocol at our trauma center incorporating neurosurgery consultation for patients with complicated mTBI led to higher rates of direct discharges from the ED and to home without compromising TBI-related follow-up care. Results demonstrate that adoption of a modified BIG protocol that includes neurosurgical collaboration can translate to more efficient […]
Timing of definitive fracture fixation in patients with concomitant traumatic brain injuries - A systematic review of the literature by the IMPACT group
CONCLUSIONS: Early definitive fracture fixation within 24 h should be attempted in polytrauma patients with concomitant mild TBI under specific conditions, which were previously defined by the IMPACT group. Furthermore, current evidence suggests that this approach is both safe and beneficial in a carefully selected patient population. In cases of moderate and severe TBI, decision-making […]