Tag:

personalized medicine

Dementia
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Overview The research focused on understanding the intricate relationship between brain network connectivity and …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Biomarkers in cerebrospinal fluid analysis Cerebrospinal fluid (CSF) serves as a crucial medium for assessing …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Metabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …

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Traumatic brain injury
N-Formylmethionine Is a Biologically Active Diagnostic Marker of Mild Traumatic Brain Injury

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Study Overview This research investigates the role of N-Formylmethionine (fMet) as a potential biomarker for …

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Headaches
Unexpected genomic architecture in a sporadic case of C1-INH Hereditary Angioedema: the hidden heritability

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Genomic Architecture Insights The genomic architecture in individuals with C1-INH Hereditary Angioedema (HAE) showcases a …

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Traumatic brain injury
Can symptom-severity phenotypes identify depression risk after mild traumatic brain injury? A cluster-based approach

by myneuronews November 4, 2025

by myneuronews November 4, 2025

Study Overview This research investigates the relationship between symptom severity phenotypes and the risk of …

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Traumatic brain injury
Mobile Health App for Adults with Persisting Postconcussion Symptoms: Development and Usability Study

by myneuronews November 4, 2025

by myneuronews November 4, 2025

Study Overview The development of a mobile health application aimed at supporting adults suffering from …

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Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …

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Headaches
Interventional Treatment Strategies for Headache and Facial Pain

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Interventional Techniques and Approaches Interventional techniques for managing headache and facial pain involve various procedures …

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Traumatic brain injury
A Comprehensive Approach to the Assessment and Management of Posttraumatic Headache

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Assessment Techniques The evaluation of individuals experiencing posttraumatic headache (PTH) is crucial for determining the …

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Establishing the link between post-concussive symptoms and brain network dysfunction: A systematic scoping review of neuroimaging evidence
Mild traumatic brain injury (mTBI) is a prevalent condition with symptoms spanning physical, psychological, cognitive, and sleep domains. Altered functional brain networks have been implicated in mTBI, but the relationship between these network changes and post-concussive symptoms remains poorly understood. This study is a systematic scoping review, adhering to PRISMA-ScR guidelines, assessing current literature on […]
Effect of prior traumatic brain injury on Alzheimer's disease blood biomarkers in Vietnam Veterans
IMPORTANCE: Traumatic brain injury (TBI) is a risk factor for dementia and is known to impact levels of several Alzheimer's disease (AD) blood biomarkers. Plasma pTau217/ Aβ42 ratio has been reported to be 90% accurate for detection of brain amyloid in civilian cohorts.
Repeated Mild Head Injury Establishes a Senescent Cranial Bone Marrow Niche that Impairs Brain Metabolism
Traumatic brain injury (TBI) of any severity is associated with long-term systemic inflammation and increased risk of peripheral comorbidities, yet the mechanisms driving immune dysregulation and accelerated aging after repeated mild head impacts remain poorly defined. Here, we investigated the acute and chronic effects of repeated mild TBI (rmTBI) on distal and proximal bone marrow […]
Commentary on "Examining and Comparing the Clinical Characteristics of Adults with Persisting Post-Concussion Symptoms Presenting for Outpatient Rehabilitation Following a Mild Traumatic Brain Injury or a Minimal Head Injury"
No abstract
Cumulative effects of mild traumatic brain injury in the general population: persistent post-concussion symptoms and post-traumatic stress
CONCLUSIONS: Multiple mTBIs are linked to increased PPCS and PTSD/C-PTSD severity in the general population. Early identification and tailored interventions are essential to reduce long-term psychological and neurological effects.