Tag:

personalized medicine

Functional neurological disorders
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Integrated Transcriptomic Insights Recent advancements in transcriptomic analysis have opened new avenues for understanding the …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Get Your Brain in the Game: Using Machine Learning to Predict Recovery Timelines Following Sports-Related Concussion

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Study Overview The research conducted aimed to investigate how machine learning can be utilized to …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Embracing the Modern Biochemistry of Brain Metabolism

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Understanding Brain Metabolism The brain is an extraordinarily energy-demanding organ, consuming approximately 20% of the …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Predicting Mental and Neurological Illnesses Based on Cerebellar Normative Features

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Cerebellar Features and Their Role in Mental Illness The cerebellum, traditionally associated with coordination and …

Read more

0 Facebook Twitter Pinterest Email
Headaches
Genome-wide associations spanning 194 in-hospital drug dosage change phenotypes highlight diverse genetic backgrounds in concurrent drug therapy

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Overview The research aimed to investigate the genetic factors influencing drug dosage adjustments during …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
OCNDS core features are conserved across variants, with loop-region mutations driving greater symptom burden

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Core Features of OCNDS OCNDS, or Obsessive-Compulsive and Nervous System Disorders, presents a set of …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Optimizing pediatric “Mild” traumatic brain injury assessments: A multi-domain random forest analysis of diagnosis and outcomes

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Overview The research examines the factors influencing the assessment, diagnosis, and outcomes associated with …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer’s disease

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Study Overview The study aimed to explore the genetic underpinnings of Alzheimer’s disease (AD) through …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Disordered Ru-O6 Octahedrons for Efficient and Selective Electro-oxidation of Sulfide to Sulfoxide via Boosted Surface Oxygen Kinetics

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Mechanism of Electro-oxidation Electro-oxidation processes are fundamental in transforming chemical compounds, particularly in promoting desirable …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
A novel cause of type 1 von Willebrand disease: impaired exocytosis of Weibel-Palade bodies due to biallelic MADD variants

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Novel Mechanism of Type 1 Von Willebrand Disease The study uncovers a previously unrecognized mechanism …

Read more

0 Facebook Twitter Pinterest Email

A sensor-based gait measure for identifying invalid performance in simulated mTBI: an experimental proof of concept
CONCLUSIONS: Findings offer preliminary support for the ability of an automated gait-based measure to capture invalid performance and inform investigations regarding effort. These experimental findings represent a first step in exploring the potential clinical utility of the BKG as a measure of performance validity.
The clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury (STOP-D): study protocol for a multi-centre randomised controlled trial
BACKGROUND: Traumatic brain injury (TBI) is a common presentation in emergency departments worldwide. Approximately 1.4 million adults present with TBI in England and Wales annually. Post-TBI depression (PTD) is a common neuropsychiatric consequence, affecting up to 50% of patients within two years, and is associated with adverse functional outcomes. PTD remains underdiagnosed and undertreated. Sertraline, […]
The Relationship of Prior Concussion and Contact Sport Exposure With Cortical Macro and Microstructure
Changes in cortical gray matter are a key feature of neurodegenerative diseases that have been linked with concussion and repetitive head impacts (RHIs). Prior evidence implicates prior concussion and RHI in reduced cortical thickness or volume in temporal and frontal regions, with results largely restricted to older retired contact sport athletes. Fewer studies have investigated […]
Impact of Modified Brain Injury Guideline Incorporating Neurosurgical Consultation on Resource Utilization and Follow-Up Care in Complicated Mild Traumatic Brain Injury
CONCLUSION: Implementation of a resource utilization-focused protocol at our trauma center incorporating neurosurgery consultation for patients with complicated mTBI led to higher rates of direct discharges from the ED and to home without compromising TBI-related follow-up care. Results demonstrate that adoption of a modified BIG protocol that includes neurosurgical collaboration can translate to more efficient […]
Timing of definitive fracture fixation in patients with concomitant traumatic brain injuries - A systematic review of the literature by the IMPACT group
CONCLUSIONS: Early definitive fracture fixation within 24 h should be attempted in polytrauma patients with concomitant mild TBI under specific conditions, which were previously defined by the IMPACT group. Furthermore, current evidence suggests that this approach is both safe and beneficial in a carefully selected patient population. In cases of moderate and severe TBI, decision-making […]