Tag:

personalized medicine

Traumatic brain injury
Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region

by myneuronews September 12, 2025

by myneuronews September 12, 2025

Study Overview The research in question investigates the effects of Spautin-1, a compound known for …

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Traumatic brain injury
Quantifying Longitudinal Microstructural Changes in Mild Traumatic Brain Injury Patients with Mean Apparent Propagator MRI

by myneuronews September 10, 2025

by myneuronews September 10, 2025

Study Overview This study investigates the microstructural changes in brain tissue associated with mild traumatic …

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Traumatic brain injury
A machine learning approach to concussive group classification using discrete outcome measures from a low-cost movement-based assessment system

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Overview of Concussive Classification Concussion, a type of traumatic brain injury, poses significant challenges for …

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Traumatic brain injury
Longitudinal Effects of Mild Traumatic Brain Injury on the Gut Microbiome and Acoustic Startle Response in Male and Female Rats

by myneuronews September 3, 2025

by myneuronews September 3, 2025

Study Overview This research investigates the consequences of mild traumatic brain injury (mTBI) on both …

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Dementia
Emerging Role of Oligodendrocytes Malfunction in the Progression of Alzheimer’s Disease

by myneuronews August 31, 2025

by myneuronews August 31, 2025

Oligodendrocyte Function and Alzheimer’s Disease Oligodendrocytes are specialized glial cells in the central nervous system, …

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Headaches
Intranasal Empagliflozin Modulates Synaptic Plasticity in Migraine: Insights into Calcium Signaling and Epigenetic Regulation

by myneuronews August 31, 2025

by myneuronews August 31, 2025

Mechanisms of Action Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, primarily functions by reducing glucose …

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Traumatic brain injury
Dynamic and Static Resting-State Functional Connectivity of Canonical Networks in Military and Civilian Populations with Posttraumatic Stress Disorder and/or Mild Traumatic Brain Injury

by myneuronews August 21, 2025

by myneuronews August 21, 2025

Study Overview This research focuses on understanding how different kinds of brain connectivity functions in …

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Traumatic brain injury
Automated Midline Shift Detection in Head CT Using Localization and Symmetry Techniques Based on User-Selected Slice

by myneuronews August 20, 2025

by myneuronews August 20, 2025

Study Overview The research focuses on the development and evaluation of an automated system for …

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Traumatic brain injury
EEG-based brain biomarker supports hyperbaric oxygen therapy for acute concussions

by myneuronews August 17, 2025

by myneuronews August 17, 2025

Brain Biomarkers and Concussions Recent advances in neuroscience have highlighted the significance of brain biomarkers …

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Headaches
Interpretable Machine Learning Integrates Multi-Source Biomarkers for Osteoarthritis Diagnosis and Mechanistic Insights: A Temporomandibular Joint Model

by myneuronews August 16, 2025

by myneuronews August 16, 2025

Study Overview This research explores the integration of diverse biomarkers through interpretable machine learning techniques …

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Establishing the link between post-concussive symptoms and brain network dysfunction: A systematic scoping review of neuroimaging evidence
Mild traumatic brain injury (mTBI) is a prevalent condition with symptoms spanning physical, psychological, cognitive, and sleep domains. Altered functional brain networks have been implicated in mTBI, but the relationship between these network changes and post-concussive symptoms remains poorly understood. This study is a systematic scoping review, adhering to PRISMA-ScR guidelines, assessing current literature on […]
Effect of prior traumatic brain injury on Alzheimer's disease blood biomarkers in Vietnam Veterans
IMPORTANCE: Traumatic brain injury (TBI) is a risk factor for dementia and is known to impact levels of several Alzheimer's disease (AD) blood biomarkers. Plasma pTau217/ Aβ42 ratio has been reported to be 90% accurate for detection of brain amyloid in civilian cohorts.
Repeated Mild Head Injury Establishes a Senescent Cranial Bone Marrow Niche that Impairs Brain Metabolism
Traumatic brain injury (TBI) of any severity is associated with long-term systemic inflammation and increased risk of peripheral comorbidities, yet the mechanisms driving immune dysregulation and accelerated aging after repeated mild head impacts remain poorly defined. Here, we investigated the acute and chronic effects of repeated mild TBI (rmTBI) on distal and proximal bone marrow […]
Commentary on "Examining and Comparing the Clinical Characteristics of Adults with Persisting Post-Concussion Symptoms Presenting for Outpatient Rehabilitation Following a Mild Traumatic Brain Injury or a Minimal Head Injury"
No abstract
Cumulative effects of mild traumatic brain injury in the general population: persistent post-concussion symptoms and post-traumatic stress
CONCLUSIONS: Multiple mTBIs are linked to increased PPCS and PTSD/C-PTSD severity in the general population. Early identification and tailored interventions are essential to reduce long-term psychological and neurological effects.