T cell-mediated immunodysregulation in multiple sclerosis: from pathogenic subsets to therapeutic advances
Pathogenic Mechanisms The role of T cells in the pathogenesis of multiple sclerosis (MS) has garnered considerable attention in recent […]
MicroRNA profiles in multiple sclerosis: A review of the literature
MicroRNA Role in Multiple Sclerosis MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a pivotal role in the regulation
MicroRNA profiles in multiple sclerosis: A review of the literature Read Post »
Predictors of relapses in patients with chronic inflammatory demyelinating polyneuropathy receiving subcutaneous immunoglobulin therapy – a post-hoc analysis
Study Overview The research focuses on chronic inflammatory demyelinating polyneuropathy (CIDP), a neurological disorder characterized by progressive weakness and sensory
Dynamic metabolic programming of monocyte-derived cells defines immunity in CNS disease
Metabolic Programming in Monocyte-Derived Cells Monocyte-derived cells, particularly macrophages and dendritic cells, undergo a process termed metabolic programming, which significantly
Dynamic metabolic programming of monocyte-derived cells defines immunity in CNS disease Read Post »
Purkinje cell-specific loss of Neurofascin and Ankyrin G causes disruption of axon initial segments, neurodegeneration, and cerebellar ataxia
Pathophysiological Mechanisms The pathophysiology underlying Purkinje cell-specific disruptions in neurofascin and ankyrin G reveals critical insights into the mechanisms that
‘No-No’ head movement as a true epileptic phenomenon – A case series with SEEG and signal processing evaluation
Study Overview This investigation delves into the phenomenon of ‘no-no’ head movement, a behavior associated with epileptic conditions that has
Identification of Alzheimer’s disease subtypes and biomarkers from human multi-omics data using subspace merging algorithm
Study Overview The research focuses on enhancing our understanding of Alzheimer’s disease through the identification of its subtypes and biomarkers
LRRK2 and GBA1 in Lewy body diseases: neuropathological subtypes at opposite ends of a spectrum?
Neuropathological Characteristics The neuropathological landscape of Lewy body diseases, such as Parkinson’s disease and dementia with Lewy bodies, is characterized
Evaluation of brain injury biomarkers in mild traumatic brain injury with and without computed tomography findings
Study Overview In recent years, the assessment of mild traumatic brain injury (mTBI) has become increasingly significant due to its
A cohort approach to focal cortical dysplasia type II: A 10-year management overview at an adult epilepsy referral centre
Study Overview The investigation focused on the management of focal cortical dysplasia type II (FCD II), a malformation of cortical