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post-traumatic epileptogenesis

Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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Bioequivalence of Two Perampanel Oral Suspension Formulations in Healthy Subjects: A Randomized Crossover Study
Study Overview The investigation focused on comparing the bioequivalence of two formulations of perampanel oral…
In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217
Study Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits…
Functional Neurological Disorder, Sleep, and Dreaming: A Large Online Questionnaire-Based Study
Background on Functional Neurological Disorder Functional Neurological Disorder (FND) encompasses a range of neurological symptoms…
Treatments for Functional Neurological Disorder: A Practical Guide for Program Development
Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) presents a unique challenge in both…
On-tools for rehabilitation and cognitive care: Development of a brief intervention for chronic cognitive difficulties after mild traumatic brain injury
Study Overview The investigation focused on addressing the often-overlooked cognitive challenges faced by individuals who…

2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila
Traumatic brain injuries (TBIs) are a global source of hospitalization, long-term disability, and death. However, age, sex, and other demographics differ widely among patients and the variable characteristics of TBIs further obscure injury outcomes. Here, we used Drosophila melanogaster to assess the effects of mild, repeated TBI (multi-day, MD) compared to single, severe TBI (single-day, […]
On-tools for rehabilitation and cognitive care: Development of a brief intervention for chronic cognitive difficulties after mild traumatic brain injury
CONCLUSION/IMPLICATIONS: Through a multistep process that incorporated stakeholder input and a review of the empirical literature, we developed an evidence-informed intervention that fills a gap in current care for cognitive PPCSs. Future studies are needed to evaluate the efficacy of this intervention for individuals with chronic cognitive difficulties after mTBI. (PsycInfo Database Record (c) 2025 […]
Comparison of Pre-injury and Clinical Characteristics Between Adolescents With Sport-Related Concussion and Non-Sport-Related Concussion Presenting to a Specialty Concussion Clinic
CONCLUSIONS: The most salient factors associated with non-SRC patients presenting to a specialty concussion clinic were a headache/migraine history, a longer time to clinic, and greater initial visit symptoms. These findings suggest that the factors that lead patients with SRC and Non-SRC to present to a specialty clinic differ, and that studies that are interested […]
Physiatry Reviews for Evidence in Practice (PREP) Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: "Context of Injury and Clinical Trajectories After Mild Traumatic Brain Injury"
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Biomarkers for prediction of chronic traumatic encephalopathy-like pathology following repeated mild traumatic brain injury in rats are partially sex- and age-dependent
INTRODUCTION: Repeated mild traumatic brain injuries (rmTBIs) pose a high risk of developing chronic traumatic encephalopathy (CTE). Since this neurodegenerative disease is diagnosed only post-mortem, new biomarkers for early detection are needed. Although age at injury and biological sex are important factors in many brain pathologies, little is known about their relevance to rmTBI-induced CTE-like […]

post-traumatic epileptogenesis

Understanding the Pathophysiology of Post-Traumatic Epilepsy