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Adverse neurologic events of immune checkpoint inhibitor monotherapy vs. combination therapy for melanoma
Study Overview The research focused on adverse neurologic events associated with the use of immune…
Multi-classification Deep Learning Approach for Diagnosing Stroke Type and Severity Using Multimodal Magnetic Resonance Images
Study Overview The study investigates the application of deep learning techniques for diagnosing various types…
Current Evidence in the Management of Central Skull Base Osteomyelitis: A Systematic Review
Study Overview Central Skull Base Osteomyelitis (CSBO) is a serious infection that affects the bony…
A Rare Case of Bilateral Xanthomatosis of Tendon of Achilles: A Case Report
Background of Bilateral Xanthomatosis Bilateral xanthomatosis is a rare condition characterized by the accumulation of…
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease
Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease…

Effect of Choline Alfoscerate on Cognitive Dysfunction After Mild Traumatic Brain Injury: A Single-Center Prospective Case-Control Study
CONCLUSION: Choline alfoscerate improves cognitive function in patients with mild traumatic brain injuries.
A systematic review and meta-analysis of sleep following mild traumatic brain injury: A synthesis of the literature according to age and time-since-injury
This systematic review and meta-analysis (PROSPERO: CRD42021287081) compared sleep in individuals with prior mTBI against that of controls. PubMed, Scopus, and EMBASE were searched through to November 2, 2024. Mean differences were calculated for objective (sleep duration, sleep efficiency, sleep stage [N1-3, REM] proportions) and subjective (Pittsburgh Sleep Quality Index [PSQI]) sleep measures, with analyses […]
Exploring trends in pediatric craniofacial furniture accidents: Implications for prevention, safety counseling, and future advocacy initiatives
CONCLUSION: Pediatric craniofacial injuries from furniture and television tip-overs remain a concern despite recent declines, particularly affecting infants and toddlers under four years old. Continued efforts are needed to address safety risks associated with tip-overs in the home and school settings.
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy
Tau protein plays a critical role in the physiological functioning of the central nervous system by providing structural integrity to the cytoskeletal architecture of neurons and glia through microtubule assembly and stabilization. Under certain pathological conditions, tau is aberrantly phosphorylated and aggregates into neurotoxic fibrillary tangles. The aggregation and cell-to-cell propagation of pathological tau leads […]
Thiamine administration and in-hospital mortality in patients with traumatic brain injury: analysis of the MIMIC-IV database
CONCLUSION: Thiamine administration may reduce in-hospital mortality for patients with TBI admitted to the ICU.