Tag:

prefrontal cortex

Traumatic brain injury
Multimodal Magnetic Resonance Imaging with Mild Repetitive Head Injury in Awake Rats: Modeling the Human Experience and Clinical Condition

by myneuronews June 29, 2025

by myneuronews June 29, 2025

Study Overview This study investigates the effects of mild repetitive head injuries on brain function …

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Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Phenotypes In chronic traumatic brain injury (TBI), individuals often manifest a variety of clinical …

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Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Distinct Clinical Phenotypes Chronic traumatic brain injury (TBI) presents a spectrum of clinical phenotypes, each …

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Dementia
Depression exacerbates AD pathology through lactate-dependent activation of microglial Kv1.3 to promote Aβ-containing exosome spreading

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Background and Rationale The intersection of depression and Alzheimer’s disease (AD) has garnered increasing attention …

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Traumatic brain injury
Depression Symptoms Associated With Clinical Symptoms, Disability, and Functional Connectivity After Traumatic Brain Injury

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Association Between Depression Symptoms and TBI Traumatic brain injury (TBI) is a significant public health …

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Traumatic brain injury
Mild Traumatic Brain Injury Impairs Fear Extinction and Network Excitability in the Infralimbic Cortex

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Study Overview The study aimed to investigate the effects of mild traumatic brain injury (mTBI) …

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Traumatic brain injury
Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury

by myneuronews May 15, 2025

by myneuronews May 15, 2025

TRPM3 Channel Function in the Brain The TRPM3 channel, a member of the transient receptor …

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Traumatic brain injury
Diffusion Tensor Image Analysis Along the Perivascular Space in Former Professional Athletes with Repetitive Mild Traumatic Brain Injury History

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Background and Rationale Understanding the implications of repetitive mild traumatic brain injuries (mTBIs) is essential, …

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Brain & Crime
The Moors Murders: A Chilling Crime and the Neurobiological Profile of Its Perpetrators

by Ioannis Mavroudis September 14, 2024

by Ioannis Mavroudis September 14, 2024

The Moors Murders: A Dark Chapter in British History The Moors Murders remain one of …

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Brain & Crime
Neurobiological Insights into the Mind of a Cold-Blooded Criminal: A Detailed Brain Analysis

by Ioannis Mavroudis September 14, 2024

by Ioannis Mavroudis September 14, 2024

One of the most horrific crimes in the history of Greece. For the way it …

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Clinical Cut Point for the Post Concussion Symptom Inventory Following Adolescent Concussion
CONCLUSIONS: Our results suggest a PCSI cut point of 23 can distinguish between adolescents with/without a recent concussion and may provide enhanced accuracy to identify a suspected concussion in the subacute time after injury.
Sex Differences in Severity and Recovery Following Mild Traumatic Brain Injury: A Systematic Review
Background: Sex-based variations in brain structure, hormonal balance, and neurochemistry may influence symptom presentation and recovery after mild traumatic brain injury (mTBI). This systematic review investigated sex-related differences in mTBI severity, symptoms, and recovery outcomes across different injury mechanisms. Methods: This review followed PRISMA 2020 guidelines and was registered with PROSPERO (CRD420251011379). Searches were conducted […]
Driving After Concussion: The Influence of Days Since Concussion on Simulated Driving Performance Recovery
CONCLUSIONS: Clinicians should consider recommendations that support limited driving during the acute stages (24-72 hours) of concussion followed by a gradual return to driving. A longitudinal study design in a larger sample is needed to better define driving performance recovery following concussion.
Non-Pharmacological Approaches to Addressing Overweight and Obesity in Children and Adolescents with Mental Illness: A Scoping Review of Quantitative and Qualitative Evidence
Children and adolescents with mental illness are at increased risk of developing overweight and obesity, a relationship that is complex, bidirectional, and often exacerbated by the weight-related side effects of psychotropic medications. This review addressed the research question: How are overweight and obesity addressed in children and adolescents with mental illness? Following JBI and PRISMA-ScR […]
A Prefrontal Neuromodulation Route for Post-Traumatic Olfactory Dysfunction: A Perspective Supported by Recovery During Left-DLPFC rTMS
Post-traumatic olfactory dysfunction (PTOD) is a common and often persistent sequela of mild traumatic brain injury (mTBI), with limited evidence-based treatment options. We propose that high-frequency rTMS applied to the left dorsolateral prefrontal cortex (DLPFC) may support olfactory recovery via top-down modulation of distributed olfactory, attentional, and reward networks, and we outline key mechanistic and […]