Tag:

prognosis

Functional neurological disorders
Dynamic electro-clinical features in Guanidinoacetate N-methyltransferase deficiency: A familial case series

by myneuronews June 21, 2025

by myneuronews June 21, 2025

Clinical Presentation and Symptoms Patients with Guanidinoacetate N-methyltransferase (GAMT) deficiency often exhibit a complex array …

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Functional neurological disorders
Tolerating Uncertainty as a Transdiagnostic Construct and Treatment Target in Functional Motor Disorder

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Tolerating uncertainty in functional motor disorder Tolerating uncertainty is a fundamental aspect of understanding and …

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Dementia
Identification of diagnostic DNA methylation markers in the blood of Japanese Alzheimer’s disease patients using methylation capture sequencing

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The research aimed to uncover specific DNA methylation markers present in the blood …

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Functional neurological disorders
Long-Term Survival in Brown-Vialetto-Van Laere Syndrome: A Case Report Highlighting Respiratory Care

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Long-Term Outcomes in Brown-Vialetto-Van Laere Syndrome Brown-Vialetto-Van Laere Syndrome (BVVLS) is a rare neurological condition …

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Traumatic brain injury
Sex-stratified patterns in geriatric patients with mild traumatic brain injury and intracranial bleeding: a retrospective cohort study

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Background Information Mild traumatic brain injury (mTBI) presents a significant public health challenge, particularly among …

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Headaches
Silent Fungal Invasion: A Case of Aspergillus Brain Abscesses in an Immunocompetent Older Adult Patient

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Case Presentation A 74-year-old male with no prior health complications was admitted to the hospital …

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Functional neurological disorders
Can artificial intelligence improve the diagnosis and prognosis of disorders of consciousness? A scoping review

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Artificial Intelligence Applications in Diagnosis Artificial intelligence (AI) has made significant inroads in various medical …

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Dementia
Retinal degeneration as an initial manifestation in a patient with neuronal intranuclear inclusion disease

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Background of Retinal Degeneration Retinal degeneration encompasses a range of conditions characterized by the progressive …

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Traumatic brain injury
The Polytrauma Clinical Triad Among Women with a History of Intimate Partner Violence

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Understanding Polytrauma Polytrauma refers to the simultaneous occurrence of multiple traumatic injuries, which can significantly …

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Traumatic brain injury
Resting-State Brain Activity Changes and Their Genetic Correlates in Mild Traumatic Brain Injury

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Overview of Resting-State Brain Activity Resting-state brain activity refers to the spontaneous fluctuations in brain …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.