Tag:

proteomics

Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes During Glial Scar Formation After a traumatic brain injury (TBI), the brain undergoes …

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Functional neurological disorders
Pantethine ameliorates dilated cardiomyopathy features in PPCS deficiency disorder in patients and cell line models

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Pantethine Effects on Cardiomyopathy Pantethine, a derivative of vitamin B5, has recently garnered attention for …

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Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Role of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …

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Functional neurological disorders
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Integrated Transcriptomic Insights Recent advancements in transcriptomic analysis have opened new avenues for understanding the …

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Traumatic brain injury
Integrative Constraint-Based Modeling and Proteomics Uncover Astrocytic Metabolic Adaptations to the Post-TBI Microenvironment

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Study Overview The research explores the metabolic responses of astrocytes, a type of glial cell …

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Functional neurological disorders
Epileptic seizure biophysics: the role of local voltage difference

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Biophysical Mechanisms of Seizures The process of a seizure can be understood through the lens …

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Dementia
Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The study examines the potential for machine-learning techniques to identify a reliable protein …

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Dementia
Metabolic changes in the one-carbon metabolism-related amino acids during etoposide-induced cellular senescence of neuronal cells

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Metabolic Alterations in Neuronal Cells Metabolic changes in neuronal cells, particularly during cellular senescence, play …

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Functional neurological disorders
Development of a novel liquid chromatography-tandem mass spectrometry based enzymatic assay of 5,10-methylenetetrahydrofolate reductase

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Enzymatic Assay Development The development of a novel enzymatic assay for 5,10-methylenetetrahydrofolate reductase (MTHFR) taps …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenic Role of Inflammatory Proteins In recent studies, inflammatory proteins have emerged as key players …

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Timing of neurorehabilitation and subsequent Alzheimer's disease risk in patients with moderate to severe traumatic brain injury: A nationwide retrospective cohort study in the United States
BackgroundTraumatic brain injury (TBI) is associated with an increased risk of Alzheimer's disease (AD). It is unknown if prompt neuro-rehabilitative treatment following moderate or severe TBI mitigates this risk compared with delayed treatment.ObjectiveTo determine whether immediate neuro-rehabilitative treatment following moderate or severe TBI reduces the risk of AD and related cognitive outcomes compared with delayed […]
War-related traumatic brain injury in Gaza: a multi-center prospective analysis of patterns and outcomes
CONCLUSION: In this cohort of war-related TBI patients in Gaza, mortality was significantly linked to admission GCS, age, brain matter extrusion, IVH, and SDH. The study highlights how resource-limited, conflict-driven healthcare disruptions impact TBI outcomes and emphasizes the need to strengthen neurosurgical capacity, emergency response systems, and rehabilitation efforts in such environments.
Radiofrequency lesioning for hemidystonia: a systematic review and meta-analysis with individual patient data
Background Radiofrequency lesioning (RL) had been a mainstay in functional neurosurgery for dystonic movement disorders before the widespread adoption of deep brain stimulation (DBS). Outcomes of RL in hemidystonia have varied. This review provides a systematic analysis of RL for hemidystonia and evaluates the spectrum of clinical outcome. Methods A systematic literature review was performed […]
The network-based underpinnings of persisting symptoms after concussion: a multimodal neuroimaging meta-analysis
Persisting symptoms after concussion (PSaC) represent a complex and poorly understood neuropsychiatric phenomenon with limited treatment options. Neural network dysfunction has been associated with PSaC, and neuromodulation, particularly repetitive transcranial magnetic stimulation, may be a promising intervention. However, neuroimaging findings have been inconsistent, limiting understanding of underlying network dysfunction. We aimed to identify a core […]
Outcomes of Spinal Manipulation and Neurological Rehabilitation for a Patient With Chronic Tension-Type Headaches and a Prior History of Head Trauma
Chronic tension-type headaches (TTH) can be a debilitating condition that may include peripheral vestibular system involvement. This case report describes the response to spinal manipulation (SM) and neurologic rehabilitation for a 44-year-old male with TTH complicated by a history of concussion. The patient presented to a chiropractic teaching clinic with over 15 years of daily […]