Tag:

proteomics

Traumatic brain injury
Non-Targeted Analysis of Extracellular Vesicle-Enriched Plasma Proteome Between Early and Late Rugby Playing Career

by myneuronews November 30, 2025

by myneuronews November 30, 2025

Study Overview This research investigates the differences in the proteomic profiles of extracellular vesicles (EVs) …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Metabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …

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Traumatic brain injury
Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Understanding Traumatic Brain Injury Severity Traumatic brain injury (TBI) manifests in varying degrees of severity, …

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Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …

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Traumatic brain injury
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in …

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Functional neurological disorders
Serum biomarkers in epilepsy: More than meets the eye

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Serum Biomarkers in Epilepsy Recent research has increasingly focused on serum biomarkers as valuable tools …

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Functional neurological disorders
Serum biomarkers in epilepsy: More than meets the eye

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Serum Biomarkers Overview Serum biomarkers have emerged as a critical aspect of understanding and diagnosing …

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Traumatic brain injury
Exercise-induced molecular modulation following mTBI: A multi-omics study in male mice

by myneuronews October 9, 2025

by myneuronews October 9, 2025

Study Overview This study investigates the effects of exercise on molecular changes following a mild …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes During Glial Scar Formation After a traumatic brain injury (TBI), the brain undergoes …

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Functional neurological disorders
Pantethine ameliorates dilated cardiomyopathy features in PPCS deficiency disorder in patients and cell line models

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Pantethine Effects on Cardiomyopathy Pantethine, a derivative of vitamin B5, has recently garnered attention for …

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Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report
Study Overview This case report focuses on a unique instance of rhomboencephalitis, an inflammation of…
Assessing the health-related quality of life in informal caregivers of Alzheimer’s Disease: evidence from Malaysia
Health-Related Quality of Life in Caregivers The health-related quality of life (HRQoL) among informal caregivers…
Using Genetics to Shed Light on the Scientific Gray Zone of Functional Seizures
Genetic Factors in Functional Seizures Recent studies have begun to uncover the genetic underpinnings that…
2025 guideline update to acute treatment of migraine for adults in the emergency department: The American Headache Society evidence assessment of parenteral pharmacotherapies
Study Overview This comprehensive review focuses on the advances in the management of acute migraine…
Knee Biomechanics in Individuals With a Recent Concussion During Jump-Landing Tasks
Background and Rationale The relationship between concussions and subsequent physical performance, particularly in biomechanical tasks,…

Riding at Risk: The Lifesaving Role of Helmets for Motorcycle Pillion Riders
CONCLUSION: Pillion riders sustain serious TBIs comparable to or more severe than riders. The mortality rate is substantial, particularly among those not wearing helmets. Mandatory helmet use for pillion riders could significantly reduce mortality and injury severity. Further comparative studies between riders and pillion riders are warranted to better understand injury patterns and develop targeted […]
Letter to the Editor in Response to: Eagle SR, Henry RJ. Applying Dynamical Systems Theory to Improve Personalized Medicine Following Mild Traumatic Brain Injury. Neurotrauma Rep 2024 Jul 16;5(1):671-679; Doi: 10.1089/Neur.2024.0040
No abstract
Ryanodex Reduces Persistent Hippocampal Effects of Single Mild Traumatic Brain Injury in Rats
Traumatic brain injury (TBI) affects millions of individuals annually, with a 53% increase in emergency visits since 2006. Despite its prevalence, no FDA-approved treatments exist to mitigate brain damage or promote recovery. While repeated TBI is widely studied, even a single impact can cause persistent neurological changes, likely mediated by Ca^(2+) dysregulation via effects on […]
Exploring Speech Biosignatures for Traumatic Brain Injury and Neurodegeneration: Pilot Machine Learning Study
CONCLUSIONS: This study highlights the potential of speech features as biomarkers for neurodegenerative conditions. The PaTaKa test exhibited strong discriminative ability, especially for concussed versus neurodegenerative and concussed versus healthy tasks, whereas challenges remain for neurodegenerative versus healthy classification. These findings emphasize the need for further exploration of speech-based tools for differential diagnosis and early […]
Evaluation of rule changes affecting head contact in North American professional ice hockey using video review of head impact frequency and magnitude between 2003-04 and 2016-17 seasons
Ice hockey is a sport with a high incidence of concussion, but growing attention has been placed on the broader exposure to head impacts, regardless of clinical symptoms, due to their potential cumulative effects. While player education, protective equipment, and rule modifications have been introduced to reduce head impact risk, the effect of rule changes […]