Tag:

proteomics

Dementia
Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The study examines the potential for machine-learning techniques to identify a reliable protein …

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Dementia
Metabolic changes in the one-carbon metabolism-related amino acids during etoposide-induced cellular senescence of neuronal cells

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Metabolic Alterations in Neuronal Cells Metabolic changes in neuronal cells, particularly during cellular senescence, play …

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Functional neurological disorders
Development of a novel liquid chromatography-tandem mass spectrometry based enzymatic assay of 5,10-methylenetetrahydrofolate reductase

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Enzymatic Assay Development The development of a novel enzymatic assay for 5,10-methylenetetrahydrofolate reductase (MTHFR) taps …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenic Role of Inflammatory Proteins In recent studies, inflammatory proteins have emerged as key players …

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Traumatic brain injury
Uncovering injury-specific proteomic signatures and neurodegenerative risks in single and repetitive traumatic brain injury

by myneuronews June 22, 2025

by myneuronews June 22, 2025

Injury-Specific Proteomic Signatures In recent research, a growing body of evidence has revealed that distinct …

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Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Headaches
Changes in metabolite profiles in the cerebrospinal fluid and in human neuronal cells upon tick-borne encephalitis virus infection

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Metabolite Profile Changes Upon infection with the tick-borne encephalitis virus (TBEV), significant alterations occur in …

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Functional neurological disorders
Advances in Diagnostic Approaches for Alzheimer’s Disease: From Biomarkers to Deep Learning Technology

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Advancements in Biomarker Identification Recent developments in the field of Alzheimer’s disease diagnostics have centered …

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Traumatic brain injury
Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biomarker Identification and Validation The identification and validation of biomarkers for traumatic brain injury (TBI) …

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Functional neurological disorders
Spatial Multiomics Toward Understanding Neurological Systems

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding Spatial Multiomics Spatial multiomics is revolutionizing our understanding of the brain and its complex …

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Impact of surgery in patients with multiple sclerosis: a nationwide cohort study
Study Overview The investigation aimed to evaluate the influence of surgical interventions on individuals diagnosed…
Effects of Electrical Stimulation Therapy for Residual Foot Drop Following Lumbar Spinal Stenosis Surgery: A Case Report
Study Overview The study investigates the effects of electrical stimulation therapy on patients suffering from…
Navigating Fabry Disease in a Military Aviator
Understanding Fabry Disease Fabry disease is a rare genetic disorder that results from a deficiency…
Pituitary Mimic: Sellar Meningioma in a Patient Undergoing Fertility Therapy
Background of Sellar Meningiomas Sellar meningiomas are a specific type of tumor that originates from…
Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) After Polypropylene Mesh Implantation – Protocol of a Pilot Study for Diagnostics and Treatment
Background of ASIA Syndrome Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) encompasses a spectrum of…

Association between concussion-reporting intention and reporting behavior in a simulated game setting
CONCLUSIONS: Concussion-reporting behavior in a novel, first-person simulated in-game experience is higher among individuals with higher baseline concussion-reporting intention. This approach may offer promise for evaluating concussion-reporting intention and concussion-reporting behavior via interactive video simulation.
A Comparison of Determinants of Musculoskeletal and Concussion Injury Disclosure in Adolescent Athletes: An Alternative Explanation for Secondary Musculoskeletal Injury Risk After Concussion
CONCLUSIONS: Intention to disclose a concussion was positively associated with intention to disclose an MSK injury. Future studies should address the effect of cross-cutting interventions to improve attitudes surrounding concussion and MSK injury disclosure that may also influence perceived social norms surrounding injury reporting.
Caregiver education as a protective factor against psychopathology following mild traumatic brain injury in youth
PURPOSE: Mild traumatic brain injury (mTBI) is a common injury in youth, and it has been shown to be related to a host of externalizing and internalizing symptoms. The long-term impact of mTBI may be greater for youth from marginalized backgrounds. Additionally, mental health symptoms present prior to the injury may also affect responses to […]
Exploring the Impact of Mitoquinone Supplementation on Glycan Profiles in a Repeated Mild Traumatic Brain Injury Mouse Model
Traumatic brain injury (TBI) represents a significant cause of injury-related deaths and disabilities. Repeated exposure to mechanical impact can lead to metabolic and ionic imbalance, which can cause oxidative stress and worsen the cellular dysfunction initiated by the initial mild TBI (mTBI). Currently, no FDA-approved drug targets repeated mTBI (rmTBI) and its potential sequelae. Mitoquinone […]
Outpatient Follow-up After Pediatric Traumatic Brain Injury at an Urban Safety Net Hospital: A Retrospective Cohort Study
CONCLUSION: Patient-centered discharge instructions with detailed service referrals increase access to critical follow-up care. Children with TBIs should have follow-up care arranged regardless of injury severity. Larger multicenter studies are needed to validate these findings.