Tag:

proteomics

Traumatic brain injury
CCL5/RANTES signaling in inflammation dysregulation after mild traumatic brain injury

by myneuronews January 8, 2026

by myneuronews January 8, 2026

CCL5/RANTES Role in Brain Injury CCL5, also known as RANTES (Regulated upon Activation, Normal T …

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Functional neurological disorders
Structural brain alterations and predictors of clinical improvement in functional cognitive disorder after concussion

by myneuronews January 7, 2026

by myneuronews January 7, 2026

Structural Brain Alterations Recent research has illuminated the intricate relationship between structural brain alterations and …

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Traumatic brain injury
Plasma biomarkers in chronic mild traumatic brain injury: A review

by myneuronews December 31, 2025

by myneuronews December 31, 2025

Biomarkers in Chronic Mild Traumatic Brain Injury Chronic mild traumatic brain injury (mTBI), commonly associated …

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Traumatic brain injury
Plasma biomarkers in chronic mild traumatic brain injury: A review

by myneuronews December 31, 2025

by myneuronews December 31, 2025

Biomarkers in Chronic Mild Traumatic Brain Injury Chronic mild traumatic brain injury (mTBI) is a …

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Traumatic brain injury
Biomarkers

by myneuronews December 26, 2025

by myneuronews December 26, 2025

Biomarker Definition and Types Biomarkers are biological indicators that provide measurable evidence of specific physiological …

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Traumatic brain injury
Biomarkers

by myneuronews December 26, 2025

by myneuronews December 26, 2025

Biomarker Definition and Types Biomarkers, or biological markers, are quantifiable indicators of biological processes, pathological …

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Traumatic brain injury
Biomarkers

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Biomarker Definition and Significance Biomarkers are measurable indicators that reflect biological processes, pathogenic processes, or …

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Traumatic brain injury
Biomarkers

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Definition and Types Biomarkers are biological indicators that provide insights into the physiological or pathological …

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Dementia
Biomarkers

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Biomarker Definition and Types Biomarkers are biological indicators that are used to measure and evaluate …

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Traumatic brain injury
Biomarkers

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Definition and Types Biomarkers are measurable indicators that reflect physiological, pathological processes, or responses to …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]
Potential Role of Serum Cytokines and Chemokines as Biomarkers of Injury Severity and Functional Outcomes Following Pediatric Traumatic Brain Injury
Traumatic brain injury (TBI) is one of the leading causes of death and neurological disability worldwide. The search for biomarkers that indicate TBI severity and prognosis with greater accuracy is ongoing. This study aimed to evaluate the significance of several neuroinflammatory cytokines and chemokines, assessing their potential as biomarkers in pediatric TBI (pTBI). This was […]
Biomarkers
CONCLUSION: These findings highlight the potential of AEV-derived inflammatory and complement proteins as biomarkers of neuroinflammation and cognitive decline in TBI-exposed aging populations. The persistence of inflammatory abnormalities in AEVs years after TBI suggests a chronic neuroinflammatory response that may underlie increased AD risk. Future work will examine interactions between inflammatory and neurodegenerative AEV biomarkers […]