Tag:

recovery outcomes

Traumatic brain injury
External validation of the modified Brain Injury Guidelines: an observational study

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Study Overview This observational study aimed to assess the effectiveness of the modified Brain Injury …

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Functional neurological disorders
Adverse life events and psychosocial stressors in functional neurological disorder: a retrospective cohort and case-control study using a large international electronic health record database

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Background and Rationale Functional Neurological Disorder (FND) encompasses a range of neurological symptoms that are …

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Traumatic brain injury
Life after traumatic brain injury: A social media analysis revealing unmet needs

by myneuronews December 23, 2025

by myneuronews December 23, 2025

Social Media Insights Social media platforms have become crucial venues for individuals with traumatic brain …

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Traumatic brain injury
Critically appraised paper: In youth with mild traumatic brain injury, early prescribed step-count focused activity, despite symptoms, and a resilience health app, provides no added benefit over standard care for improving symptoms or quality of life [synopsis]

by myneuronews December 20, 2025

by myneuronews December 20, 2025

Study Overview The research aimed to evaluate the effectiveness of a specific intervention for young …

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Traumatic brain injury
Moderate and severe traumatic brain injury: lesion frequency distribution maps and prognostic importance of brain contusions on early MRI

by myneuronews December 19, 2025

by myneuronews December 19, 2025

Lesion Frequency Distribution Maps Lesion frequency distribution maps are critical tools in the study of …

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Traumatic brain injury
Neurotrauma induced retinal basement membrane COL4A1 defects are restored by adipose tissue derived mesenchymal stem cell concentrated conditioned medium

by myneuronews December 16, 2025

by myneuronews December 16, 2025

Study Overview The study investigates the effects of neurotrauma on the retinal basement membrane, specifically …

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Traumatic brain injury
A comprehensive review on adaptive plasticity and recovery mechanisms post-acquired brain injury

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Adaptive Plasticity Mechanisms Adaptive plasticity refers to the brain’s ability to reorganize itself in response …

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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Research Context The brain is a complex organ with numerous cellular interactions, and understanding these …

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Functional neurological disorders
Revisiting Psychopathological Hand as a Functional Neurological Disorder : Time to Reframe?

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Reconceptualizing Psychopathological Hand The concept of psychopathological hand presents a complex interplay between psychological factors …

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Traumatic brain injury
Gaps in Access to Cognitive Rehabilitation Referrals Among Veterans with Mild Traumatic Brain Injury

by myneuronews December 12, 2025

by myneuronews December 12, 2025

Access Barriers to Rehabilitation Numerous obstacles can hinder veterans with mild traumatic brain injury (mTBI) …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]