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  • Traumatic brain injury

    Use of In-Hospital Mild Traumatic Brain Injury Symptom Checklist Within 24 Hours of Injury to Predict 3-Month Symptom Outcome

    by myneuronews November 26, 2025
    by myneuronews November 26, 2025

    Study Overview The research investigates the utility of a specific tool, the In-Hospital Mild Traumatic …

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  • Traumatic brain injury

    Assessment of quality of life after traumatic brain injury in adults from Armenia, Georgia, and Moldova using EQ-5D-5L

    by myneuronews November 25, 2025
    by myneuronews November 25, 2025

    Assessment Results The assessment of quality of life following traumatic brain injury (TBI) in adults …

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  • Traumatic brain injury

    The Intensive Stroke Cycling for Optimal Recovery and Economic Value Trial (I-SCORE): Protocol for a Randomized Clinical Trial

    by myneuronews November 25, 2025
    by myneuronews November 25, 2025

    Study Overview The Intensive Stroke Cycling for Optimal Recovery and Economic Value Trial (I-SCORE) is …

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  • Traumatic brain injury

    A Clinical Practice Guideline for Adults With Concussion/Mild TBI: We Can’t Wait Until 2042

    by myneuronews November 24, 2025
    by myneuronews November 24, 2025

    Background and Rationale To understand the importance of addressing concussion and mild traumatic brain injury …

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  • Traumatic brain injury

    The kynurenine pathway in pediatric “mild-to-moderate” traumatic brain injury: translational insights from a prospective human study and a large-animal model

    by myneuronews November 21, 2025
    by myneuronews November 21, 2025

    Kynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid …

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  • Traumatic brain injury

    Impact of prior concussion history on concussion symptoms and health-related quality of life in an underrepresented and historically excluded population

    by myneuronews November 21, 2025
    by myneuronews November 21, 2025

    Impact of Concussion History Research has shown that individuals with a history of concussions may …

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  • Traumatic brain injury

    Transitions in Independent Living, Productivity, and Social Relationships Among Individuals Sustaining Traumatic Brain Injury in Adolescence: A TBI Model Systems Investigation

    by myneuronews November 21, 2025
    by myneuronews November 21, 2025

    Study Overview The investigation focused on the trajectories of independent living, productivity, and social interactions …

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  • Traumatic brain injury

    Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review

    by myneuronews November 19, 2025
    by myneuronews November 19, 2025

    Clinical Outcomes in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant challenge in …

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  • Functional neurological disorders

    Complex dissociation following maternal suicide attempt in a 17-year-old female: a case report

    by myneuronews November 19, 2025
    by myneuronews November 19, 2025

    Case Presentation and Background The case study focuses on a 17-year-old female who presented with …

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  • Traumatic brain injury

    2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila

    by myneuronews November 18, 2025
    by myneuronews November 18, 2025

    Study Overview The investigation centers around understanding how innate immune signaling influences the outcomes of …

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  • Sildenafil provokes headache but not migraine in men with migraine without aura: a randomized, placebo-controlled crossover trial
    Study Overview The research aimed to investigate the effects of sildenafil, a phosphodiesterase type 5…
  • Associations of Lifetime Cumulative Estrogen Exposure with Lifecourse Social Exposures, Cognitive Decline, and Dementia Risk Among Postmenopausal White, Black, and Latina Women
    Lifetime Estrogen Exposure and Cognitive Health Lifetime estrogen exposure has emerged as a significant factor…
  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Incretin Mimetics Mechanism of Action Incretin mimetics are agents that are designed to mimic the…
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Study Overview This investigation focuses on the effects of N-stearidonoylethanolamine (NSE) in addressing synaptic deficits…
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    Study Overview This study investigates the long-term effects of persistent post-concussion symptoms (PPCS) on various…

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Research

  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
  • Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
    CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
  • Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
    Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]

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