Tag:

recovery outcomes

Traumatic brain injury
N-Formylmethionine Is a Biologically Active Diagnostic Marker of Mild Traumatic Brain Injury

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Study Overview This research investigates the role of N-Formylmethionine (fMet) as a potential biomarker for …

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Traumatic brain injury
Three-Month Outcomes of Traumatic Brain Injury in the General Population: A Sunnybrook Traumatic Brain Injury Cohort Study

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Study Overview The investigation examines the aftermath of traumatic brain injuries (TBIs) within a diverse …

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Traumatic brain injury
A novel multimodal pharmacologic approach using guanfacine, N-acetylcysteine, and donepezil in severe TBI: a case series

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Study Overview This study presents a novel approach to treating severe traumatic brain injury (TBI) …

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Headaches
Microsurgical Management of Anterior Inferior Cerebellar Artery Aneurysms: Case Series and Review of Advanced Imaging and Cranial Base Approaches

by myneuronews November 9, 2025

by myneuronews November 9, 2025

Background and Significance Aneurysms associated with the anterior inferior cerebellar artery (AICA) are relatively rare …

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Traumatic brain injury
Using the Modified Vestibular/Ocular Motor Screening Tool to Identify Blast Exposure Effects in Military Service Members

by myneuronews November 9, 2025

by myneuronews November 9, 2025

Background of Blast Exposure Blast exposure has become a significant concern in military settings, especially …

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Traumatic brain injury
Therapeutic VEGFC treatment provides protection against traumatic-brain-injury-driven tauopathy pathogenesis

by myneuronews November 8, 2025

by myneuronews November 8, 2025

Therapeutic Efficacy of VEGFC The treatment of traumatic brain injury (TBI) has been a significant …

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Traumatic brain injury
Linking Symptom Phenotypes to Patterns of White Matter Injury in Mild Traumatic Brain Injury: A Latent Class Analysis

by myneuronews November 7, 2025

by myneuronews November 7, 2025

Study Overview The study investigates how symptom patterns in individuals with mild traumatic brain injury …

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Traumatic brain injury
Head injuries in Iceland: Analysis of visits to Landspitali University Hospital for head injuries, 2010-2023

by myneuronews November 7, 2025

by myneuronews November 7, 2025

Study Overview This study focuses on head injuries in Iceland, specifically analyzing the data from …

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Traumatic brain injury
Optimal movement behaviours for postconcussion symptom recovery in children and adolescents: a compositional analysis of the PedCARE cohort

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Optimal Movement Behaviours Optimal movement behaviours are pivotal in facilitating recovery from postconcussion symptoms in …

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Traumatic brain injury
Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Understanding Traumatic Brain Injury Severity Traumatic brain injury (TBI) manifests in varying degrees of severity, …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]