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research

Traumatic brain injury
External validation of the modified Brain Injury Guidelines: an observational study

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Study Overview This observational study aimed to assess the effectiveness of the modified Brain Injury …

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Traumatic brain injury
Pittsburgh Brain Health Initiative (BHI): protocol and methods for an observational study of cognitive function in former professional football players and controls

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Study Overview The Pittsburgh Brain Health Initiative aims to investigate cognitive function among former professional …

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Traumatic brain injury
Biomarkers

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Definition and Types Biomarkers are measurable indicators that reflect physiological, pathological processes, or responses to …

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Functional neurological disorders
Adverse life events and psychosocial stressors in functional neurological disorder: a retrospective cohort and case-control study using a large international electronic health record database

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Adverse Life Events in FND Recent investigations into Functional Neurological Disorder (FND) have highlighted a …

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Functional neurological disorders
Towards a Latin American neuropsychiatry: challenges and opportunities

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Current Landscape of Neuropsychiatry in Latin America The landscape of neuropsychiatry in Latin America is …

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Functional neurological disorders
Adverse life events and psychosocial stressors in functional neurological disorder: a retrospective cohort and case-control study using a large international electronic health record database

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Background and Rationale Functional Neurological Disorder (FND) encompasses a range of neurological symptoms that are …

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Functional neurological disorders
Towards a Latin American neuropsychiatry: challenges and opportunities

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Current Landscape of Neuropsychiatry in Latin America The practice of neuropsychiatry in Latin America is …

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Functional neurological disorders
Adverse life events and psychosocial stressors in functional neurological disorder: a retrospective cohort and case-control study using a large international electronic health record database

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Adverse Life Events and Psychosocial Stressors In exploring the relationship between adverse life events and …

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Functional neurological disorders
Towards a Latin American neuropsychiatry: challenges and opportunities

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Overview of Neuropsychiatry in Latin America Neuropsychiatry in Latin America is a unique and evolving …

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Functional neurological disorders
Adverse life events and psychosocial stressors in functional neurological disorder: a retrospective cohort and case-control study using a large international electronic health record database

by myneuronews December 24, 2025

by myneuronews December 24, 2025

Adverse Life Events in Functional Neurological Disorder Research on Functional Neurological Disorder (FND) has increasingly …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]