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research

Functional neurological disorders
Functional cervical dystonia: diagnostic accuracy of distinct clinical features

by myneuronews December 17, 2025

by myneuronews December 17, 2025

Clinical Characteristics of Cervical Dystonia Cervical dystonia, a common type of focal dystonia, manifests as …

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Traumatic brain injury
The risk of all-cause injury and site-specific injury in athletes after concussion: a systematic review and meta-analysis

by myneuronews December 16, 2025

by myneuronews December 16, 2025

Study Overview The systematic review and meta-analysis explored the consequences of concussion in athletes, specifically …

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Traumatic brain injury
Ultra-high contrast MRI: a new technique for recognizing secondary changes to the brain in patients with persistent symptoms following traumatic brain injury

by myneuronews December 16, 2025

by myneuronews December 16, 2025

Ultra-high Contrast MRI Technique The development of ultra-high contrast magnetic resonance imaging (MRI) represents a …

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Traumatic brain injury
Attention-Deficit/Hyperactivity Disorder Following Mild Traumatic Brain Injury in Children: A Retrospective Exploratory Study

by myneuronews December 16, 2025

by myneuronews December 16, 2025

Understanding ADHD Post-TBI Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by persistent patterns of …

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Traumatic brain injury
Hollow CuS nanocubes enhance serum metabolic profiles for rapid diagnosis and severity grading of traumatic brain injury

by myneuronews December 16, 2025

by myneuronews December 16, 2025

Study Overview The investigation centers on the innovative application of hollow copper sulfide (CuS) nanocubes …

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Traumatic brain injury
Neurotrauma induced retinal basement membrane COL4A1 defects are restored by adipose tissue derived mesenchymal stem cell concentrated conditioned medium

by myneuronews December 16, 2025

by myneuronews December 16, 2025

Study Overview The study investigates the effects of neurotrauma on the retinal basement membrane, specifically …

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Functional neurological disorders
Revisiting Psychopathological Hand as a Functional Neurological Disorder : Time to Reframe?

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Understanding Psychopathological Hand Psychopathological hand refers to a perplexing condition in which patients experience abnormal …

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Dementia
Event segmentation applications in large language model enabled automated recall assessments

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Application of Event Segmentation Event segmentation is a technique that allows for the organization of …

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Headaches
The P2Y13 receptor-mediated microglial morphological transformation through the p38MAPK signaling pathway contributes to central sensitization in a murine model of chronic migraine

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview The primary objective of this research was to investigate the role of the …

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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Research Context The brain is a complex organ with numerous cellular interactions, and understanding these …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]