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research

Traumatic brain injury
Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The ADEPT trial is designed to investigate the effectiveness of accelerated intermittent theta …

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Traumatic brain injury
Microstructural Damage Progression in the Pia-Arachnoid Complex

by myneuronews June 29, 2025

by myneuronews June 29, 2025

Microstructural Changes Observed The study of microstructural changes within the pia-arachnoid complex reveals a complex …

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Traumatic brain injury
Multimodal Magnetic Resonance Imaging with Mild Repetitive Head Injury in Awake Rats: Modeling the Human Experience and Clinical Condition

by myneuronews June 29, 2025

by myneuronews June 29, 2025

Study Overview This study investigates the effects of mild repetitive head injuries on brain function …

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Traumatic brain injury
Health care utilization and cost in the dual diagnosis of combined traumatic spinal cord injury and traumatic brain injury compared to traumatic brain injury alone: An analysis using MarketScan

by myneuronews June 28, 2025

by myneuronews June 28, 2025

Study Overview The research investigates the healthcare utilization and associated costs among patients diagnosed with …

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Functional neurological disorders
Functional Syndromes in the Pediatric Population and Their Rehabilitation Management: Chronic Pain Syndrome and Functional Neurologic Disorder

by myneuronews June 28, 2025

by myneuronews June 28, 2025

Understanding Functional Syndromes Functional syndromes encompass a range of medical conditions where psychological or neurological …

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Traumatic brain injury
Pediatric Mild Traumatic Brain Injury and Concussion

by myneuronews June 28, 2025

by myneuronews June 28, 2025

Understanding Mild Traumatic Brain Injury in Pediatric Patients Pediatric mild traumatic brain injury (mTBI), commonly …

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Functional neurological disorders
Mental disorders in military personnel at the stage of medical care in a multidisciplinary military medical organization

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Mental Health Challenges in Military Personnel Mental health challenges in military personnel are a significant …

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Functional neurological disorders
Lesion distribution and network mapping in dyskinetic cerebral palsy

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Lesion characteristics in dyskinetic cerebral palsy Dyskinetic cerebral palsy (CP) is a complex condition characterized …

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Functional neurological disorders
Myeloproliferative syndrome as a cause of chorea

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Myeloproliferative Syndromes Overview Myeloproliferative syndromes (MPS) are hematologic disorders characterized by the excessive production of …

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Functional neurological disorders
Modulation of conformational features and oligomerization of MMACHC by cobalamin variants: impact of the R161Q mutation in cblC disease

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Conformational Features of MMACHC The study delves into the conformational characteristics of MMACHC, a protein …

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Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip
Traumatic brain injuries (TBIs) are a risk factor for Alzheimer's disease (AD), and share several important pathological features including the development of neurofibrillary tangles (NFT) of tau protein. While this association is well established, the underlying pathogenesis is poorly defined and current treatment options remain limited, necessitating novel methods and approaches. In response we developed […]
Detecting mild traumatic brain injury with MEG scan data: One-vs-K-sample tests
Magnetoencephalography (MEG) scanner has been shown to be more accurate than other medical devices in detecting mild traumatic brain injury (mTBI). However, MEG scan data in certain spectrum ranges can be skewed, multimodal, and heterogeneous which can mislead the conventional case-control analysis that requires the data to be homogeneous and normally distributed within the control […]
Risk of Mortality Among Adult Females Diagnosed with Traumatic Brain Injury in an Academic Medical System
The objective of this retrospective cohort study was to evaluate mortality risk over five years among 6,432 female patients with a health care encounter diagnosis of TBI from hospitals and outpatient clinics within a university health system. We used TBI severity, defined by the Centers for Disease Control and Department of Defense/Veterans Affairs: mild, moderate/severe/penetrating, […]
CD300f enables microglial damage sensing, efferocytosis, and apoptotic cell metabolization after brain injury
Microglia, the resident phagocytes of the central nervous system (CNS), continuously survey the parenchyma and its borders, acting as first responders to brain injury. Their ability to detect and react to environmental changes is mediated by a repertoire of surface receptors collectively known as themicroglial sensome. Here, we identify the lipid-sensing immunoreceptor CD300f as a […]
The prognostic value of a screening tool for psychological risk factors after mild traumatic brain injury: prospective studies in Canada and New Zealand
CONCLUSION: The STarT-C-a brief screening tool-predicted persistent symptoms and disability in adults following mTBI. The incremental prognostic value of the STarT-C over the RPQ may be variable, but regardless, the tool may be useful for identifying those at risk of prolonged recovery who may benefit from early psychological intervention.