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salivary biomarkers

Biomarkers Traumatic brain injury
Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

by Ioannis Mavroudis November 16, 2024

by Ioannis Mavroudis November 16, 2024

Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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Biomarkers Medical professionals Traumatic brain injury
Salivary biomarkers in Post-concussion syndrome

by Ioannis Mavroudis February 12, 2024

by Ioannis Mavroudis February 12, 2024

Traumatic brain injuries (TBIs), particularly mild TBIs, present a complex diagnostic challenge due to their …

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Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury
Clinical Phenotypes In chronic traumatic brain injury (TBI), individuals often manifest a variety of clinical…
Wearable-Derived Patterns of Performance Fatigability During Gait in Spinal Muscular Atrophy
Wearable Technology Insights Wearable technology has significantly advanced the understanding of physical performance and health…
Association of white blood cell count-to-mean platelet volume ratio with the risk of fatal stroke occurrence in older Chinese
Study Overview The research focused on the relationship between the ratio of white blood cell…
The global burden of swine influenza and its mitigation
Global Impact of Swine Influenza Swine influenza, primarily caused by the H1N1 virus, has emerged…
Daily, prospective associations between sleep architecture and affect: insights from Bayesian multilevel compositional data analysis
Study Overview This research investigates the relationship between various aspects of sleep architecture and emotional…

Quantification of the cerebral pressure-flow relationship directional sensitivity: Reliability of shorter repeated squat-stand durations
The magnitude of changes in middle cerebral artery mean blood velocity (MCAv) is attenuated when mean arterial pressure (MAP) increases compared with when MAP decreases. This directional sensitivity has been characterized using a time-corrected ratio calculated on MCAv and MAP changes induced by repeated squat-stands (RSS) at 0.05 and 0.10 Hz for 300 s (∆MCAv(T)/∆MAP(T)). […]
A Comparison of Quantitative Pupillometry and VOMS in Division 1 Female Soccer Players
Background and Objectives: Vision uses about half of the pathways within the brain, and these anatomical structures are susceptible to injury in concussion. Authors have suggested that subconcussive head impacts, common in soccer, may disrupt visual function. The following study aimed to explore and compare quantitative pupillometry and Vestibular Ocular Motor Screening (VOMS) in female […]
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury
Accumulating evidence of heterogeneous long-term outcomes after traumatic brain injury (TBI) has challenged longstanding approaches to TBI outcome classification that are largely based on global functioning. A lack of studies with clinical and biomarker data from individuals living with chronic (>1 year post-injury) TBI has precluded refinement of long-term outcome classification ontology. Multimodal data in […]
Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]

salivary biomarkers

Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

Salivary biomarkers in Post-concussion syndrome