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salivary biomarkers

  • BiomarkersTraumatic brain injury

    Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

    by Ioannis Mavroudis November 16, 2024
    by Ioannis Mavroudis November 16, 2024

    Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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  • BiomarkersMedical professionalsTraumatic brain injury

    Salivary biomarkers in Post-concussion syndrome

    by Ioannis Mavroudis February 12, 2024
    by Ioannis Mavroudis February 12, 2024

    Traumatic brain injuries (TBIs), particularly mild TBIs, present a complex diagnostic challenge due to their …

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  • Differences of the 6N and 6J Substrains of C57BL/6 Mice in the Development of Experimental Autoimmune Encephalomyelitis
    Study Overview The research focuses on understanding the differences in the susceptibility to experimental autoimmune…
  • Preventive strategies for reducing intraoperative awareness due to errors in anesthetic drug delivery systems: a narrative review
    Study Overview The focus of the narrative review is to examine strategies aimed at minimizing…
  • Frequency of Fals and Degree of Diability in Stroke Patients
    Frequency of Fals in Stroke Patients Research has shown that the occurrence of falls among…
  • The efficacy and safety of intrathecal pemetrexed for leptomeningeal metastasis from non-small cell lung cancer: a single-arm meta-analysis of Chinese patients
    Study Overview This study focuses on evaluating the effectiveness and safety of intrathecal pemetrexed in…
  • Defense mechanisms in immune-mediated diseases: a cross-sectional study focusing on Severe Allergic Asthma and Hymenoptera Venom Anaphylaxis patients
    Study Overview The investigation aimed to explore the immune system’s response mechanisms in patients suffering…

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Research

  • Aldehydic load as an objective imaging biomarker of mild traumatic brain injury
    Mild traumatic brain injury (mTBI) is neurological impairment induced by biomechanical forces without structural brain damage, currently without an objective diagnostic tool. Downstream injury stems from oxidative damage leading to the production of neurotoxic aldehydes. A collagen-based 3D corticomimetic in vitro model of concussion was developed, confirming aldehyde production following impact. Total aldehyde levels were […]
  • Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures
    Service members and law enforcement personnel are frequently exposed to blast overpressure during training and combat due to the use of heavy weaponry such as large-caliber rifles, explosives, and ordnance. The cumulative effects of these repeated low-level (
  • Plasma levels of biomarkers associated with vasodilation and neuroinflammation in pediatric patients with head trauma and their relationship with clinical characteristics of patients
    CONCLUSION: Evaluation of pediatric patients with head trauma together with these neuropeptides may provide great benefits in deciding whether to perform radiography such as CT. However, due to the relatively low sensitivities in ROC analysis and small sample size, further studies are warranted before they may be used as a screening test to distinguish CT-positive […]
  • Trajectories of fear avoidance behavior and recovery after mild traumatic brain injury: Findings from the Toronto Concussion Study
    CONCLUSION: Early fear avoidance behavior often decreases, but when it does not, it is associated with worse recovery from mTBI. These findings may inform the timing and design of interventions targeting fear avoidance behavior in patients with mTBI. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
  • Proposed Reformulation of Brain Injury Criteria (BrIC) Using Head Rotation-Induced Brain Injury Thresholds Simulated and Derived Directly from A Subhuman Primate Finite Element Model
    Recent studies have found that Brain Injury Criteria (BrIC) grossly overpredicts instances of real-world, severe traumatic brain injury (TBI). However, as it stands, BrIC is the leading candidate for a rotational head kinematics-based brain injury criteria for use in automotive regulation and general safety standards. This study attempts to understand why BrIC overpredicts the likelihood […]

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