Tag:

signs

Dementia
Resistance and resilience to Alzheimer’s disease in Down syndrome

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Understanding Alzheimer’s Disease in Down Syndrome Alzheimer’s disease (AD) is a multifaceted neurodegenerative condition characterized …

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Headaches
Tuberculous meningitis initially presented with low levels of pleocytosis and protein in the cerebrospinal fluid: a case report

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Clinical Presentation In this case report, a patient initially presented with symptoms that are often …

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Functional neurological disorders
MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging Clinical Implications-A Review

by myneuronews April 26, 2025

by myneuronews April 26, 2025

MTHFR Gene Polymorphisms and Their Role in Health The MTHFR gene, which stands for methylene …

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Traumatic brain injury
Computed Tomography Findings of Children Under 3 Years of Age with Mild Traumatic Brain Injury (TBI) and No Neurological Focal Signs

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Computed Tomography Characteristics Computed tomography (CT) plays a crucial role in evaluating pediatric patients with …

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Traumatic brain injury
Mild Traumatic Brain Injury in Children: What Parents Need to Know

by Ioannis Mavroudis April 26, 2025

by Ioannis Mavroudis April 26, 2025

Mild traumatic brain injury (mTBI), often referred to as a child concussion, can be difficult …

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Traumatic brain injury
Sport-Related Concussions in High School Athletes: A Comprehensive Update

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Understanding Concussions in High School Sports Concussions have become a significant concern in high school …

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Traumatic brain injury
Point-of-Care Electroencephalography in Acute Neurological Care: A Narrative Review

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Application of Point-of-Care EEG Point-of-care electroencephalography (POC EEG) has emerged as a transformative tool in …

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Traumatic brain injury
Clinical manifestations and treatment of hypopituitarism due to traumatic brain injury

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Understanding Hypopituitarism Hypopituitarism is a condition characterized by the insufficient production of one or more …

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Traumatic brain injury
Sickness absence > 14 days following mild traumatic brain injuries from traffic accidents: a Swedish nationwide register study

by myneuronews April 24, 2025

by myneuronews April 24, 2025

Background and Rationale Mild traumatic brain injuries (mTBIs), commonly referred to as concussions, are often …

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Decreased IL-33 in the brain following repetitive mild traumatic brain injury contributes to cognitive impairment by inhibiting microglial phagocytosis
CONCLUSIONS: Dysfunction of the IL-33/ST2 axis following rmTBI leads to cognitive dysfunction via impairing microglial phagocytosis capacity and promoting neuronal damage. IL-33 would be a promising therapeutic target for alleviating neurodegeneration following rmTBI.
Multidisciplinary rehabilitation and follow-up for children hospitalized with traumatic brain injury
PurposeMost children hospitalized with traumatic brain injury (TBI) acquire new impairments that impact function and health-related quality of life. However, there is a lack of standardized, multidisciplinary, longitudinal rehabilitative services for children with TBI.MethodsThis single center, retrospective study evaluated rehabilitative services during acute hospitalization and identified the frequency of unmet needs, defined as new or […]
Tackle characteristics associated with concussion in elite men's rugby union: unpicking the differences between tacklers and ball-carriers
CONCLUSIONS: Lower tackles reduce the chances of concussion to ball-carriers. The influence of tackle height on concussion to tacklers is more nuanced, but the chances are relatively low when contact is made with the ball-carrier's torso. These findings support ongoing implementation of strategies to reduce concussion risk by lowering tackle height to target the torso.
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model
Repetitive mild traumatic brain injury (rmTBI) is a major contributor to long-term neurological dysfunction, yet many preclinical models lack precise control and quantification of biomechanical forces across impacts. We developed a reproducible, closed-skull mouse model of rmTBI using a custom-built weight-drop apparatus featuring a solenoid-based rebound arrest system, integrated high-speed videography, and accelerometry to track […]
Pretreatment with an anti-CGRP monoclonal antibody attenuates mild TBI-induced tactile hypersensitivity in mice
CONCLUSIONS: These results indicate that an anti-CGRP mAb can partially, but not fully, attenuate cephalic tactile hypersensitivity when administered immediately before or after the mTBI event. In contrast, a stronger rescue was seen when the anti-CGRP mAb was administered just prior to CGRP and nitric oxide triggers. Thus, depending on the timing of administration, the […]