Tag:

study population

Movement Disorders
Effects of GBA1 Variants in Patients With Parkinson’s Disease and Levodopa-Carbidopa Intestinal Gel: A Nation-Wide, Multicenter, Longitudinal, “Real-World” Study. The EPIC Study

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Study Overview The EPIC Study was designed to investigate the impact of GBA1 gene variants …

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Traumatic brain injury
Outpatient Follow-up After Pediatric Traumatic Brain Injury at an Urban Safety Net Hospital: A Retrospective Cohort Study

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Study Overview The investigation into outpatient follow-up care after pediatric traumatic brain injury (TBI) at …

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Traumatic brain injury
A double-blind, placebo-controlled, randomized, multi-centre, phase III study of MLC901 (NeuroAiDTMII) for the treatment of cognitive impairment after mild traumatic brain injury

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Study Overview The clinical trial investigated the efficacy of MLC901, also known as NeuroAiD II, …

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Stroke
Arterial stiffness and atherosclerosis and incident cardiovascular events and all-cause mortality in individuals with manifest cardiovascular disease with and without type 2 diabetes

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The investigation centers on the interplay between arterial stiffness and atherosclerosis, particularly how …

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Traumatic brain injury
The Predictive Value of Heart Rate Variability for the Prognosis of Patients with Mild to Moderate Traumatic Brain Injury

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Predictive Value of Heart Rate Variability Heart rate variability (HRV) refers to the fluctuations in …

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Headaches
The efficacy and safety of intrathecal pemetrexed for leptomeningeal metastasis from non-small cell lung cancer: a single-arm meta-analysis of Chinese patients

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This study focuses on evaluating the effectiveness and safety of intrathecal pemetrexed in …

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Functional neurological disorders
Abnormal static and dynamic regional homogeneity in adolescent major depressive disorder with somatic symptoms: a resting-state fMRI study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Methodological Overview The study employs a resting-state functional magnetic resonance imaging (fMRI) approach to examine …

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Traumatic brain injury
Aldehydic load as an objective imaging biomarker of mild traumatic brain injury

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Aldehydic Load Measurement The measurement of aldehydic load plays a crucial role in understanding the …

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Functional neurological disorders
Identification of comorbid genes between type 2 diabetes and migraine through peripheral blood single-cell and Mendelian randomization analysis

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Comorbid Gene Identification The identification of comorbid genes linking type 2 diabetes and migraine is …

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Traumatic brain injury
Long-Term Health-Related Quality of Life and Perceptions of Recovery in Adults Who Received Clinical Profiles Informed Care for Concussion

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Long-Term Quality of Life Outcomes Long-term health-related quality of life (HRQoL) outcomes for adults who …

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Immunological Tolerance Induced by Nanoliposome with Autoantigenie Peptide and Artesunate to Inhibit Complement and Remodel Immune Balance for Multiple Sclerosis Treatment
Study Overview The research investigates the potential of using nanoliposomes as a delivery system for…
Neuromuscular Blockade Efficacy in High Elastance ARDS: Signal or Statistical Noise?
Study Overview This research investigates the efficacy of neuromuscular blockade in patients exhibiting high elastance…
The Association of a Polygenic Lifespan Score With the Risk of Common Age-Related Diseases and Mortality
Study Overview The research investigates the relationship between a polygenic lifespan score—derived from multiple genetic…
Comparing patient-reported symptoms and structured clinician documentation in electronic health records
Symptom Reporting Comparisons Research into the differences between symptoms reported by patients and those documented…
Clinical Characterization and Long-Term Outcome in Children and Adults With Anti-AMPA Receptor Encephalitis
Clinical Presentation The clinical presentation of anti-AMPA receptor encephalitis is characterized by a diverse array…

Bedside Ultrasonographic Measurement of Optic Nerve Sheath Diameter for Assessing Increased Intracranial Pressure: An Observational Study
Background Traumatic brain injury (TBI) is a leading cause of disability and mortality, particularly in resource-limited settings where advanced neuromonitoring tools are often unavailable. Elevated intracranial pressure (ICP) is a serious and potentially life-threatening complication of TBI. Traditional methods for monitoring ICP are invasive, expensive, and require specialized expertise. Ultrasonographic measurement of the optic nerve […]
Early-Life Mild Traumatic Brain Injury Alters Neurodevelopment and Behavior in Mice
Approximately 280 children per 100,000 experience closed-head injuries each year, with over 80% being mild in severity. While most children with mild injuries do not require admission to a hospital and recover well over time, some children experience persistent behavioral and cognitive abnormalities that continue into adolescence. Mild traumatic brain injury (mTBI) during early life […]
Optimizing pediatric "Mild" traumatic brain injury assessments: A multi-domain random forest analysis of diagnosis and outcomes
CONCLUSIONS: Clinicians should adopt a tailored approach for clinical assessments across different post-injury intervals to enhance clinical care, shorten assessment batteries, and better understand recovery in children with "mild" TBI.
Instrumented Dual-Task Tests Help for Concussion Assessment in Ice Hockey
CONCLUSION: DT assessments can detect residual cognitive impairments even after other clinical symptoms have resolved. These tests offer medical staff objective insights, facilitating informed decision-making during the return-to-play process.
Objective Versus Subjective Cognitive Status Following Mild Traumatic Brain Injury: The Role of Psychological Factors
CONCLUSIONS: Consistent with prior research, elevated psychological symptoms burden was associated with higher subjective cognitive complaints in relation to objective cognitive abilities. These results highlight the continued need for psychological intervention in post-mTBI recovery.