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Traumatic brain injury
Psychiatric outcomes after mild concussion by treatment timing and age

by myneuronews May 18, 2025

by myneuronews May 18, 2025

Background and Rationale The relationship between mild concussions and subsequent psychiatric outcomes is an area …

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Functional neurological disorders
Scar-associated macrophages and biliary epithelial cells interaction exacerbates hepatic fibrosis in biliary atresia

by myneuronews May 18, 2025

by myneuronews May 18, 2025

Mechanisms of Macrophage and Biliary Epithelial Cell Interaction The interaction between macrophages and biliary epithelial …

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Traumatic brain injury
Modelling and Standardisation of EHR Data for Mild Traumatic Brain Injury Patient Management

by myneuronews May 17, 2025

by myneuronews May 17, 2025

Background and Rationale The landscape of healthcare has witnessed a rapid transformation with the advent …

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Functional neurological disorders
Gene replacement therapy to restore polyamine metabolism in a Snyder-Robinson syndrome mouse model

by myneuronews May 17, 2025

by myneuronews May 17, 2025

Restoration of Polyamine Metabolism The restoration of polyamine metabolism represents a pivotal intervention in the …

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Functional neurological disorders
Loneliness in Parkinson’s disease: Subjective experience overshadows objective motor impairment

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Understanding Loneliness in Parkinson’s Disease Loneliness is a profound and complex emotion that frequently accompanies …

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Functional neurological disorders
The role of immunotherapy in a refractory case of acute hemorrhagic leukoencephalitis in a pediatric patient

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Clinical Presentation and Diagnosis In evaluating a pediatric patient presenting with acute hemorrhagic leukoencephalitis (AHLE), …

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Functional neurological disorders
Unveiling diverse clinical symptom patterns and neural activity profiles in major depressive disorder subtypes

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Clinical Symptom Patterns in Major Depressive Disorder In the realm of mental health, Major Depressive …

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Traumatic brain injury
Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury

by myneuronews May 15, 2025

by myneuronews May 15, 2025

TRPM3 Channel Function in the Brain The TRPM3 channel, a member of the transient receptor …

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Traumatic brain injury
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Overview of Neurophysiological Mechanisms Understanding the neurophysiological mechanisms underlying concussion involves delving into the complex …

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Traumatic brain injury
Injury Prevention Programs in Youth Football: A Narrative Review of the FIFA 11+ and FUNBALL Programs

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Program Framework and Objectives The FIFA 11+ program and the FUNBALL initiative are both structured …

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Guillain-Barré Syndrome Induced by Mycoplasma Pneumoniae: A Non-classical Presentation
Study Overview This study investigates a unique case of Guillain-Barré Syndrome (GBS) that arose following…
The Role of Metabolic Testing in the Diagnostic Evaluation of Adult NORSE: A Retrospective, Single-Centre Study
Study Overview The study under discussion investigates the significance of metabolic testing in diagnosing non-acute…
Alcohol Intake and Cardiovascular Outcomes in Patients With Atrial Fibrillation: RE-LY AF Registry Analysis
Study Overview The analysis derived from the RE-LY AF registry explores the implications of alcohol…
Long-term outcomes in leucine-rich glioma inactivated-1 autoimmune encephalitis and associated biomarkers of inflammation and neuronal and glial injury
Long-term outcomes Long-term outcomes in patients with leucine-rich glioma inactivated-1 (LGI1) autoimmune encephalitis are a…
Understanding personal preferences to promote exercise adherence in Parkinson’s disease
Understanding Preferences for Exercise Exploring individuals’ exercise preferences is essential in tailoring interventions that resonate…

Persistent Post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies
INTRODUCTION: Persistent post-concussion syndrome (PCS) following mild traumatic brain injury (mTBI) represents a growing global health challenge that significantly impacts patients' quality of life. Despite advances in acute concussion management, there remains a critical need for effective, evidence-based treatments for chronic PCS, as current interventions show limited success in addressing both symptoms and underlying pathophysiology.
Time-limited association between plasma transfusion and mortality in pediatric traumatic brain injury
CONCLUSION: This study reports a significant association between early plasma administration and a lower risk of 4-hour mortality among children with severe TBI that does not persist at or beyond 24 hours. While these data suggest that plasma resuscitation may extend the window for lifesaving intervention, additional prospective data are needed.
Comparing the sensitivity and specificity of novel motor assessments for traumatic brain injury
CONCLUSION: MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.
Cellular mechanisms of traumatic brain injury
Mild traumatic brain injury (mTBI) is an acute injury with immediate and medium-term symptom presentation. However, our mechanistic understanding of mTBI and how mechanical loading of soft cellular tissues leads to injury is limited. The aim of this review is to introduce this interdisciplinary field to non-experts and provide an overview of our current understanding […]
Chronic Traumatic Encephalopathy Neuropathologic Change Is Not Associated With Suicide in Former Athletes
There are important knowledge gaps and misunderstandings relating to chronic traumatic encephalopathy (CTE). A systematic review and meta-analysis, published in April of 2025, was designed to examine the prevalence, risk factors, and potential outcomes of CTE neuropathologic change (CTE-NC) in former athletes and concluded that suicide was a potential outcome of CTE-NC (Qi et al., […]