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Functional neurological disorders
Identifying pyroptosis- and inflammation-related genes in spinal cord injury based on bioinformatics analysis

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Gene Identification Methods To identify genes that play a role in pyroptosis and inflammation following …

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Functional neurological disorders
A scoping review of studies on dissociative and conversion disorders in India

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Overview of Dissociative and Conversion Disorders Dissociative and conversion disorders represent complex and often misunderstood …

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Traumatic brain injury
Musculoskeletal Injuries in National Hockey League Goaltenders

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Prevalence of Injuries Research indicates that goaltenders in the National Hockey League (NHL) face a …

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Functional neurological disorders
Extrapyramidal symptoms as early clinical predictors in first-episode schizophrenia and schizophreniform disorder: findings from the OPTiMiSE trial

by myneuronews July 13, 2025

by myneuronews July 13, 2025

Extrapyramidal Symptoms in First-Episode Schizophrenia Extrapyramidal symptoms (EPS) represent a group of movement disorders that …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP The role of ALOX5AP (Arachidonate 5-Lipoxygenase Activating Protein) in the pathogenesis …

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Traumatic brain injury
A one year longitudinal study of cortical myelination changes following pediatric mild traumatic brain injury

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Cortical Myelination Changes The study of cortical myelination following pediatric mild traumatic brain injury (mTBI) …

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Traumatic brain injury
Integrative Constraint-Based Modeling and Proteomics Uncover Astrocytic Metabolic Adaptations to the Post-TBI Microenvironment

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Study Overview The research explores the metabolic responses of astrocytes, a type of glial cell …

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Traumatic brain injury
Attention-Deficit/Hyperactivity Disorder as a Mediating Variable for Invalid Baseline Profiles on the ImPACT

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Study Overview The research investigates the role of Attention-Deficit/Hyperactivity Disorder (ADHD) as a mediating factor …

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Traumatic brain injury
Repetitive head impact exposure in collegiate wrestling practices using instrumented mouthguard technology

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Study Overview The research focused on the exposure to repetitive head impacts experienced by collegiate …

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Dementia
Creutzfeldt-Jakob Disease in South Texas: A Case Series of Three Hispanic Patients

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Study Overview This study examines a rare and debilitating neurodegenerative disorder, Creutzfeldt-Jakob Disease (CJD), as …

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Autologous bone marrow mononuclear cell administration for neurological sequelae after traumatic brain injury: a matched control study
Neurological sequelae after traumatic brain injury impair motor and behavioural functions, imposing a heavy burden on patients and society. Traditional treatments show limited efficacy, highlighting the need for advanced therapies. This study evaluated the safety and efficacy of intrathecal administration of bone marrow mononuclear cells for treating these sequelae. A matched control clinical trial was […]
Concussion Classification in a Multicenter Patient Cohort: The Updated ACRM Diagnostic Criteria and Concordance With Physician Impression of Injury
CONCLUSION: Use of the ACRM criteria clinically to determine if an injury qualifies as mTBI may be less susceptible to bias from ongoing symptom reporting than the physician impression of the injury.
Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients
CONCLUSIONS: S100B and the GFAP/UCH-L1 combination demonstrated very high sensitivities, close to 100 %, with specificities of approximately 30 % for the diagnosis of intracranial lesions. Age-adjusted thresholds improve specificity in older patients, supporting their clinical implementation. This study also provides the first evidence that hemolysis significantly elevates UCH-L1 concentrations from 400 mg/L of hemoglobin.
Retired contact sports athletes with cognitive concerns: promoting lifelong brain health
There is widespread concern among former athletes about the link between head injury and dementia. Neurologists are increasingly assessing ex-contact sports athletes with cognitive and behavioural issues following repetitive head impacts and traumatic brain injury. Their assessment and management can be challenging due to the broad differential diagnosis, including psychiatric issues, trauma-related impairment and, in […]
Visible signs of possible concussion at the FIFA World Cup Qatar 2022: Independent review and inter-rater reliability
CONCLUSIONS: Visible signs of concussion categorized as "red flags" were infrequent, resulting in uncertain reliability. The frequency and reliability of visible signs categorized as "yellow flags" and "other signs" varied, with the visible signs "clutching of the head" and "slow to get up" occurring so frequently that their utility for identifying possible concussion in football […]