Tag:

symptoms

Movement Disorders
Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single-center open-label clinical phase I trial (NEON trial)

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Study Overview The study aimed to investigate the safety and tolerability of intravenous liposomal GM1 …

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Headaches
Efficacy and Safety of Sodium Oxybate in Adults With Idiopathic Hypersomnia: A Randomized Controlled Trial

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Efficacy of Sodium Oxybate Sodium oxybate, a central nervous system depressant, has shown promise in …

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Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Traumatic brain injury
Correction: Cerebral Haemodynamic Assessment Following Sport-related Concussion (Mild Traumatic Brain Injury) in Youth and Amateur Rugby Union Players

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Cerebral haemodynamics in concussion Cerebral haemodynamics refers to the dynamics of blood flow within the …

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Traumatic brain injury
Changes in Coping Skills Throughout Concussion Recovery in College-Aged Individuals

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Coping Skills Assessment The evaluation of coping skills among college-aged individuals recovering from concussions is …

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Traumatic brain injury
Acute Changes in Sleep Stages Following Concussion in Collegiate Athletes: A Pilot Study

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Study Overview This pilot study investigates the immediate effects of concussion on the sleep patterns …

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Functional neurological disorders
Research Progress on BDNF and Depression

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding BDNF’s Role in Depression Brain-derived neurotrophic factor (BDNF) is a protein that plays a …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Movement Disorders
A Rare Case of Bilateral Xanthomatosis of Tendon of Achilles: A Case Report

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Background of Bilateral Xanthomatosis Bilateral xanthomatosis is a rare condition characterized by the accumulation of …

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Headaches
Current Evidence in the Management of Central Skull Base Osteomyelitis: A Systematic Review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Study Overview Central Skull Base Osteomyelitis (CSBO) is a serious infection that affects the bony …

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Traumatic brain injury graphing: A case study of Charles Whitman
Research has identified violent behavior (i.e., assault, murder, and suicide) as a possible sequela of moderate to severe traumatic brain injury (TBI) and repeated mild TBI (rmTBI). However, misconceptions about consciousness and its ability to control an injured brain, the diverse spectrum of potential outcomes, and the role genetics/environmental factors can play make proving TBI's […]
Injury Prevention Programs in Youth Football: A Narrative Review of the FIFA 11+ and FUNBALL Programs
Football (soccer) is a dynamic sport popular among youth, but it poses risks of injuries such as ligament tears, fractures, and concussions. Injury prevention programs are essential for safeguarding young athletes' health and performance. This review evaluates two key programs: the 11+ and FUNBALL. The 11+ program is a structured warm-up designed for young female […]
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory
Every time a person sustains a blow to the head, they receive multiple atypical sensory inputs, often including pain. These directly stimulate the central nervous system. Yet, sensory input as a causal agent of neurophysiological dysfunction and post-concussion symptoms has never been explored. A new theory is proposed of sensory driven neurophysiological mechanisms of concussion […]
Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury
Although tumor necrosis factor-alpha (TNF-α) plays an important role in the development of obsessive-compulsive disorder (OCD), the pathogenesis remains unclear. Since transient receptor potential melastatin 3 (TRPM3) channels are activated during inflammatory conditions, crosstalk with TNF-α in the progression of OCD has not been investigated yet. We hypothesize that mild traumatic brain injury (mTBI) stimulates […]
Age-Adjusted Cut-Off Values for Glial Fibrillary Acidic Protein and Ubiquitin Carboxy-Terminal Hydrolase L1 Improve the Diagnostic Accuracy of the Abbott Mild Traumatic Brain Injury Assay
Objectives: To establish age-adjusted cut-off values for glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) and assess their impact on the diagnostic performance of the mild traumatic brain injury (mTBI) assay. Methods: The study included 175 adult mTBI patients presenting at the emergency department (ED) within 12 h from head trauma in […]