Tag:

symptoms

Movement Disorders
Distinct inflammatory profiles in young-onset versus late-onset Alzheimer’s disease

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Inflammatory Profiles in Alzheimer’s Disease Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-beta …

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Headaches
Laparoscopic Adrenal Surgery in an Adolescent Boy in the Caribbean With Malignant Hypertension Secondary to Pheochromocytoma: A Case Report and Literature Review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Case Background The subject of this case study is a young male adolescent, presenting with …

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Stroke
Circulating Immune Cell Signature Analysis in HFpEF Across Species

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The investigation into circulating immune cell signatures in heart failure with preserved ejection …

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Functional neurological disorders
Polycystic ovary syndrome as a risk factor for cancer

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Risk Factors Associated with Polycystic Ovary Syndrome Polycystic ovary syndrome (PCOS) is characterized by a …

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Functional neurological disorders
Cognitive Analytic Therapy for Functional/Dissociative Seizures in an Adolescent: Case Report and Mixed-Methods Single-Case Evaluation

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Case Overview The case in question involves a 15-year-old adolescent presenting with functional seizures, also …

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Functional neurological disorders
Disease Progression in Children With Friedreich Ataxia: Functional Performance and Other Outcome Assessments in the FACHILD Study

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Disease Characteristics and Symptoms Friedreich Ataxia (FA) is a hereditary degenerative disease characterized primarily by …

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Dementia
Cortical inhibitory and facilitatory alterations in the continuum of alpha-synucleinopathies

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Cortical Inhibition in Alpha-Synucleinopathies Alterations in cortical inhibition have been observed in alpha-synucleinopathies, which include …

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Movement Disorders
Electroencephalography and polysomnography as predictors of long-term functional outcomes in anti-CASPR2 encephalitis: A multicenter cohort study

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research investigates the relationship between electrophysiological assessments—specifically electroencephalography (EEG) and polysomnography (PSG)—and …

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Functional neurological disorders
Gut microbiota and myelination: Crosstalk across the lifespan and microbiota-based modulation strategies

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Gut Microbiota’s Role in Myelination The gut microbiota, a complex community of microorganisms residing in …

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Functional neurological disorders
Polycystic ovary syndrome as a risk factor for cancer

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Understanding Polycystic Ovary Syndrome Polycystic Ovary Syndrome (PCOS) is a complex hormonal disorder that affects …

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Decreased IL-33 in the brain following repetitive mild traumatic brain injury contributes to cognitive impairment by inhibiting microglial phagocytosis
CONCLUSIONS: Dysfunction of the IL-33/ST2 axis following rmTBI leads to cognitive dysfunction via impairing microglial phagocytosis capacity and promoting neuronal damage. IL-33 would be a promising therapeutic target for alleviating neurodegeneration following rmTBI.
Multidisciplinary rehabilitation and follow-up for children hospitalized with traumatic brain injury
PurposeMost children hospitalized with traumatic brain injury (TBI) acquire new impairments that impact function and health-related quality of life. However, there is a lack of standardized, multidisciplinary, longitudinal rehabilitative services for children with TBI.MethodsThis single center, retrospective study evaluated rehabilitative services during acute hospitalization and identified the frequency of unmet needs, defined as new or […]
Tackle characteristics associated with concussion in elite men's rugby union: unpicking the differences between tacklers and ball-carriers
CONCLUSIONS: Lower tackles reduce the chances of concussion to ball-carriers. The influence of tackle height on concussion to tacklers is more nuanced, but the chances are relatively low when contact is made with the ball-carrier's torso. These findings support ongoing implementation of strategies to reduce concussion risk by lowering tackle height to target the torso.
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model
Repetitive mild traumatic brain injury (rmTBI) is a major contributor to long-term neurological dysfunction, yet many preclinical models lack precise control and quantification of biomechanical forces across impacts. We developed a reproducible, closed-skull mouse model of rmTBI using a custom-built weight-drop apparatus featuring a solenoid-based rebound arrest system, integrated high-speed videography, and accelerometry to track […]
Pretreatment with an anti-CGRP monoclonal antibody attenuates mild TBI-induced tactile hypersensitivity in mice
CONCLUSIONS: These results indicate that an anti-CGRP mAb can partially, but not fully, attenuate cephalic tactile hypersensitivity when administered immediately before or after the mTBI event. In contrast, a stronger rescue was seen when the anti-CGRP mAb was administered just prior to CGRP and nitric oxide triggers. Thus, depending on the timing of administration, the […]