Tag:

Tau

Dementia
Plasma extracellular vesicles and phosphorylated tau 181 as early biomarkers of cognitive impairment in Alzheimer’s dementia

by myneuronews January 6, 2026

by myneuronews January 6, 2026

Study Overview The focus of this research is on exploring the potential of plasma extracellular …

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Dementia
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

by myneuronews January 4, 2026

by myneuronews January 4, 2026

Study Overview The research focuses on the role of GASDERMIN D in the context of …

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Traumatic brain injury
Plasma biomarkers in chronic mild traumatic brain injury: A review

by myneuronews December 31, 2025

by myneuronews December 31, 2025

Biomarkers in Chronic Mild Traumatic Brain Injury Chronic mild traumatic brain injury (mTBI), commonly associated …

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Traumatic brain injury
Biomarkers

by myneuronews December 26, 2025

by myneuronews December 26, 2025

Biomarker Definition and Types Biomarkers, or biological markers, are quantifiable indicators of biological processes, pathological …

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Traumatic brain injury
Biomarkers

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Biomarker Definition and Significance Biomarkers are measurable indicators that reflect biological processes, pathogenic processes, or …

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Traumatic brain injury
Biomarkers

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Definition and Types Biomarkers are measurable indicators that reflect physiological, pathological processes, or responses to …

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Dementia
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants

by myneuronews December 23, 2025

by myneuronews December 23, 2025

Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a …

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Dementia
Consideration of sex as a biological variable over the history of the 5xFAD Alzheimer’s Disease mouse model

by myneuronews December 17, 2025

by myneuronews December 17, 2025

Biological Considerations When investigating Alzheimer’s disease through animal models, particularly the 5xFAD mouse model, it …

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Dementia
Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective

by myneuronews December 13, 2025

by myneuronews December 13, 2025

Background on Genetic Frontotemporal Dementia Genetic frontotemporal dementia (FTD) is a group of neurodegenerative disorders …

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Dementia
The CSF Levels of Mitochondrial Phosphoenolpyruvate Carboxykinase 2 as a Novel Biomarker in Alzheimer’s Disease

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The research focuses on the role of mitochondrial phosphoenolpyruvate carboxykinase 2 (PEPCK-M) levels …

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Current trends and projections for potential acupuncture needs globally and in China: evidence from the Global Burden of Disease Study 2021
Global Acupuncture Needs Assessment The assessment of global acupuncture needs involves a multi-faceted approach that…
Plasma extracellular vesicles and phosphorylated tau 181 as early biomarkers of cognitive impairment in Alzheimer’s dementia
Study Overview The focus of this research is on exploring the potential of plasma extracellular…
Development and Evaluation of Upper Extremity Movement Quality Outcome Measures for Individuals with Functional Movement Disorder
Methodology for Movement Quality Assessment The study employed a comprehensive methodology for assessing upper extremity…
The Clinical Utility of a Novel Multimodal Assessment Battery for Acute Sport-Related Concussion
Assessment Framework The evaluation of acute sport-related concussions necessitates a multidimensional approach that integrates various…
Associations of Symptomatic Head Trauma/Concussion Diagnosis with Sleep-Related Outcomes in Children
Study Background The relationship between head trauma and its subsequent effects on children’s sleep patterns…

Management of the paediatric patient with acute head trauma
Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
Neuroimaging correlates of symptom burden and functional recovery following mild traumatic brain injury: A systematic review
CONCLUSIONS: Acute MRI, when contextualised with clinical data, helps delineate correlates of mTBI symptom burden and functional recovery. To strengthen inference, future neuroimaging studies should prespecify and report symptom burden and functional recovery as core endpoints.
Structural brain alterations and predictors of clinical improvement in functional cognitive disorder after concussion
Functional cognitive disorder (FCD) is an under-studied yet likely prevalent subtype of functional neurological disorder (FND), with neural mechanisms that remain poorly understood. While studies of other FND subtypes have revealed structural and functional brain alterations across several large-scale brain networks, no study to date has investigated neural alterations in FCD. Here, we examined structural […]
Long-term health outcomes of adolescent mTBI: a scoping review
CONCLUSION: This review provides insight into the potential long-term concerns of adolescent mTBI and highlights areas needing further research for more robust conclusions. The review identifies critical considerations for health professionals when assessing adolescents with mTBI and creating recovery plans to promote full recovery with limited long-term impact.
Exploring sports-related concussion awareness and response amongst teenage grassroots soccer players in the UK: a qualitative study
CONCLUSIONS: Effective SRC management requires tailored education programs to overcome barriers and promote safety within grassroots youth soccer. Addressing gender norms and enhancing education can foster a culture of support and accountability, safeguarding the well-being of young athletes. There is a need for better awareness and more precautionary behaviors among all stakeholders in grassroots soccer.