Tag:

Tau

Dementia
Plasma biomarkers for early detection of alzheimer’s disease: a cross-sectional study in a Japanese cohort

by myneuronews June 7, 2025

by myneuronews June 7, 2025

Study Overview This research focuses on identifying plasma biomarkers that can facilitate the early detection …

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Functional neurological disorders
A 2025 update on treatment strategies for the Alzheimer’s disease spectrum

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Current Treatment Approaches The treatment landscape for Alzheimer’s disease has evolved considerably, reflecting a multifaceted …

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Functional neurological disorders
Advances in Diagnostic Approaches for Alzheimer’s Disease: From Biomarkers to Deep Learning Technology

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Advancements in Biomarker Identification Recent developments in the field of Alzheimer’s disease diagnostics have centered …

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Functional neurological disorders
Fully biodegradable dendrimers as novel nanodrugs for amyloid-β-induced neurotoxicity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Material and Methods The study on fully biodegradable dendrimers as novel nanodrugs targeting amyloid-β-induced neurotoxicity …

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Functional neurological disorders
Regulating aggregation of an intrinsically disordered chaperone-like casein

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Characterization of Intrinsically Disordered Chaperone-Like Casein The study of intrinsically disordered proteins (IDPs) has become …

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Movement Disorders
Evaluating the Homogeneity of the PSP-RS Syndrome beyond Core Features

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Evaluate the Homogeneity of PSP-RS Syndrome The Progressive Supranuclear Palsy-Richardson Syndrome (PSP-RS) represents a specific …

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Movement Disorders
Associations Between Changes in Levels of Phosphorylated Tau and Severity of Cognitive Impairment in Early Alzheimer Disease

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Research Objectives The primary aim of this study is to explore the relationship between fluctuations …

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Stroke
Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Study Overview The research focused on the relationship between olfactory function and Alzheimer’s disease (AD), …

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Dementia
Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Link Between Olfaction and Neurodegeneration The sense of smell, or olfaction, has been increasingly recognized …

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Functional neurological disorders
Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Association of Apoc1 with Alzheimer’s Disease Recent research has underscored the significance of the apolipoprotein …

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Understanding factors influencing the return to physical activity, perspectives of adults with concussion/mild traumatic brain injury: A qualitative study
Understanding the factors that influence the return to physical activity can help to modify behaviour to enhance the recovery of symptoms and physical activity. We conducted 14 semi-structured interviews to explore the barriers and facilitators to returning to physical activity in adults following a mild traumatic brain injury (TBI). The study design was informed by […]
Clinical Utility of the Sport Concussion Office Assessment Tool 6 (SCOAT6) and Other Select Multidomain Assessments for Subacute Sport-Related Concussion
CONCLUSIONS: The PCSI, timed tandem gait, and mVOMS components of the SCOAT6 were useful in identifying sport-related concussion. However, verbal cognitive tests, orthostatic vital signs, and clinical balance components were not useful for this purpose. The CP Screen, additional items from the full version of the VOMS, and ImPACT memory and processing speed were also […]
Persistent Post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies
INTRODUCTION: Persistent post-concussion syndrome (PCS) following mild traumatic brain injury (mTBI) represents a growing global health challenge that significantly impacts patients' quality of life. Despite advances in acute concussion management, there remains a critical need for effective, evidence-based treatments for chronic PCS, as current interventions show limited success in addressing both symptoms and underlying pathophysiology.
Time-limited association between plasma transfusion and mortality in pediatric traumatic brain injury
CONCLUSION: This study reports a significant association between early plasma administration and a lower risk of 4-hour mortality among children with severe TBI that does not persist at or beyond 24 hours. While these data suggest that plasma resuscitation may extend the window for lifesaving intervention, additional prospective data are needed.
Comparing the sensitivity and specificity of novel motor assessments for traumatic brain injury
CONCLUSION: MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.