Study Overview The research focuses on the role of mitochondrial phosphoenolpyruvate carboxykinase 2 (PEPCK-M) levels …
Tag:
Tau
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Traumatic brain injury
Long intervals between repetitive concussions reduce risk of cognitive impairment and limit microglial activation, astrogliosis, and tauopathy in adolescent rats
by myneuronewsby myneuronewsImpact of Concussion Intervals on Cognitive Outcomes Research indicates that the timing between concussive events …
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Dementia
In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217
by myneuronewsby myneuronewsStudy Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits …
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Traumatic brain injury
Biomarkers for prediction of chronic traumatic encephalopathy-like pathology following repeated mild traumatic brain injury in rats are partially sex- and age-dependent
by myneuronewsby myneuronewsStudy Overview The research embarked on an investigation into the long-term effects of repeated mild …
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Traumatic brain injury
Chronic Traumatic Encephalopathy Neuropathologic Change in Military Veterans
by myneuronewsby myneuronewsPathophysiology of Chronic Traumatic Encephalopathy Chronic Traumatic Encephalopathy (CTE) is a degenerative brain disease commonly …
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Traumatic brain injury
Therapeutic VEGFC treatment provides protection against traumatic-brain-injury-driven tauopathy pathogenesis
by myneuronewsby myneuronewsTherapeutic Efficacy of VEGFC The treatment of traumatic brain injury (TBI) has been a significant …
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Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis
by myneuronewsby myneuronewsIdentifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …
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Traumatic brain injury
Repetitive head impacts, repeat concussions, and chronic traumatic encephalopathy: Introductory editorial for a special issue
by myneuronewsby myneuronewsRepetitive head impacts and their effects Repetitive head impacts, often experienced in contact sports and …
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Traumatic brain injury
Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip
by myneuronewsby myneuronewsStudy Overview This research focuses on the cellular mechanisms involved in concussive injuries, specifically examining …
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Traumatic brain injury
Boston University Alzheimer’s Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer’s disease and related dementias
by myneuronewsby myneuronewsResearch Objectives The primary aim of the Boston University Alzheimer’s Disease Research Center’s Clinical Core …