Tag:

Tau

Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological tau phosphorylation mechanisms Tau is a critical protein in the brain, primarily known for …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Traumatic brain injury
Collision Sports and Neurodegenerative Disease: Inclusion of Moderating Risk Factors

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Impact of Collision Sports on Neurodegenerative Risk Participation in collision sports can have significant implications …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Dementia
FOXG1 Improves Cognitive Function in Alzheimer’s Disease by Promoting Endogenous Neurogenesis

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Impact of FOXG1 on Neurogenesis The role of FOXG1 in neurogenesis is increasingly being recognized …

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Functional neurological disorders
Chemical imaging delineates Aβ plaque polymorphism across the Alzheimer’s disease spectrum

by myneuronews April 24, 2025

by myneuronews April 24, 2025

Aβ Plaque Polymorphism Overview Amyloid-beta (Aβ) plaques are characteristic features found in the brains of …

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Biomarkers Traumatic brain injury
Blood biomarkers in mTBI

by Ioannis Mavroudis June 22, 2024

by Ioannis Mavroudis June 22, 2024

Several studies have demonstrated that elevated levels of S100B, GFAP, UCH-L1, and NFL correlate with …

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Daytime napping and nighttime sleep and motoric cognitive risk syndrome among Chinese older adults: a nationwide cohort study
Study Overview The study investigates the relationship between daytime napping and nighttime sleep patterns, focusing…
Juvenile systemic lupus erythematosus complicated with posterior reversible encephalopathy syndrome: a case report and literature review
Clinical Presentation Juvenile systemic lupus erythematosus (JSLE) often manifests with a range of clinical symptoms…
Social Determinants of Health Influence Mild Traumatic Brain Injury Symptom Burden: A Retrospective Study
Study Overview This study investigates the impact of social determinants on individuals experiencing mild traumatic…
Revealing gender differences in concussion reporting: a detailed analysis of SCAT assessment self-report symptom ratings
Gender Differences in Symptom Reporting Research has increasingly highlighted the complexities associated with concussion symptoms…
Head injuries in Iceland: Analysis of visits to Landspitali University Hospital for head injuries, 2010-2023
Head Injury Statistics Between 2010 and 2023, head injuries recorded at Landspitali University Hospital in…

Therapeutic VEGFC treatment provides protection against traumatic-brain-injury-driven tauopathy pathogenesis
Traumatic brain injury (TBI) increases one's risk of developing Alzheimer's disease and tauopathy. Yet, the mechanisms linking TBI to neurodegenerative disease remain poorly defined. Mounting recent evidence indicates that defects in brain lymphatic drainage contribute to multiple neurodegenerative diseases. Here, we investigated whether promoting brain lymphatic drainage recuperation following TBI via treatment with the lymphangiogenic […]
Trends in Public Knowledge Pertaining to Traumatic Brain Injury From 2016 to 2025
CONCLUSIONS: High rates of TBI misconceptions remain and individuals remain vulnerable to the impact of the spread of misinformation across mass and social media.
Social Determinants of Health Influence Mild Traumatic Brain Injury Symptom Burden: A Retrospective Study
CONCLUSION: In addition to the expected patient and injury characteristics, fraction living in poverty was a significant variable contributing to scores on the RPQ-3 and RPQ-13. Efforts to incorporate screening for SDOH factors should be considered to identify patients at risk of poor recovery after mild TBI.
Revealing gender differences in concussion reporting: a detailed analysis of SCAT assessment self-report symptom ratings
INTRODUCTION: Current concussion assessments used by the NCAA are generally applied to both male and female athletes to evaluate the effects of sports-related head impacts. However, increasing evidence indicates that female athletes show different physiological and psychosocial responses to concussions compared to their male counterparts, raising concerns about the suitability of gender blind concussion assessments.
Head injuries in Iceland: Analysis of visits to Landspitali University Hospital for head injuries, 2010-2023
CONCLUSION: Despite the reduction in head injury cases in recent years, head injuries remain a substantial public health problem. Strengthened epidemiological data collection is needed to support policymaking, especially for vulnerable age groups. There is a growing need for integrated services for both older adults and young people in risk groups.