Tag:

TBI

Traumatic brain injury
AQP4 in cerebrospinal fluid correlates with severity and prognosis in moderate to severe traumatic brain injury

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Background and Rationale Traumatic brain injury (TBI) is a significant public health concern, often resulting …

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Traumatic brain injury
Post-Traumatic Epilepsy After Mild and Moderate Traumatic Brain Injury: A Narrative Review and Development of a Clinical Decision Tool

by myneuronews October 24, 2025

by myneuronews October 24, 2025

Study Overview This review article examines the complex relationship between post-traumatic epilepsy (PTE) and mild …

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Traumatic brain injury
Clinical Evaluation of the TBI Assay in a Representative Emergency Department Cohort

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Study Overview The evaluation centered on the efficacy and reliability of the TBI Assay within …

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Traumatic brain injury
Pre-injury sleep disturbance as a moderator of cognitive functioning in children and adolescents with mild traumatic brain injury

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Study Overview The research investigates the complex interplay between pre-injury sleep disturbances and cognitive outcomes …

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Traumatic brain injury
Advancements in neurosurgical techniques for managing sports-related traumatic brain injuries

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Neurosurgical Innovations In recent years, significant strides have been made in neurosurgical techniques aimed at …

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Traumatic brain injury
Bleeding Risk With Atrial Fibrillation, Prostate Cancer Screening, Alzheimer Disease, Concussion, Melanoma, Rheumatoid Arthritis

by myneuronews October 21, 2025

by myneuronews October 21, 2025

Bleeding Risk Assessment in Atrial Fibrillation Assessing the risk of bleeding in patients with atrial …

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Traumatic brain injury
“Talk and die” syndrome, a tragedy in traumatic brain injury: a cohort study

by myneuronews October 20, 2025

by myneuronews October 20, 2025

Understanding “Talk and Die” Syndrome “Talk and Die” syndrome is a critical phenomenon observed in …

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Traumatic brain injury
Functional Connectivity Changes in Traumatic Brain Injury: A Systematic Review and Coordinate-Based Meta-Analysis of fMRI Studies

by myneuronews October 17, 2025

by myneuronews October 17, 2025

Study Overview The research focuses on the alterations in functional connectivity resulting from traumatic brain …

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Traumatic brain injury
Diagnostic and prognostic role of serum/plasma and CSF amyloid beta peptide levels in traumatic brain injury: a systematic review and meta-analysis

by myneuronews October 11, 2025

by myneuronews October 11, 2025

Background and Rationale Traumatic brain injury (TBI) represents a significant public health issue, with far-reaching …

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Traumatic brain injury
Exploring the use of manual therapy in the management of traumatic brain injury: a scoping review

by myneuronews October 11, 2025

by myneuronews October 11, 2025

Study Overview This scoping review investigates the role of manual therapy in managing traumatic brain …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]