Tag:

TBI

Traumatic brain injury
Enteral feeding initiation and feeding practices in pediatric traumatic brain injury patients admitted to the neurotrauma intensive care unit

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Nutrition Assessment Assessing the nutritional status of pediatric patients with traumatic brain injuries is crucial …

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Traumatic brain injury
Timing of neurorehabilitation and subsequent Alzheimer’s disease risk in patients with moderate to severe traumatic brain injury: A nationwide retrospective cohort study in the United States

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Study Overview The research undertaken in this study addresses the critical intersection between neurorehabilitation timing …

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Traumatic brain injury
War-related traumatic brain injury in Gaza: a multi-center prospective analysis of patterns and outcomes

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Epidemiology of traumatic brain injury Traumatic brain injury (TBI) represents a substantial public health challenge …

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Traumatic brain injury
Enteral feeding initiation and feeding practices in pediatric traumatic brain injury patients admitted to the neurotrauma intensive care unit

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Feeding Protocols In the management of pediatric traumatic brain injury (TBI) patients, establishing effective feeding …

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Traumatic brain injury
Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients

by myneuronews October 8, 2025

by myneuronews October 8, 2025

Study Overview This study examined the efficacy of three biomarkers—GFAP (Glial Fibrillary Acidic Protein), UCH-L1 …

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Traumatic brain injury
Plumbagin Alleviates Mild Traumatic Brain Injury-Induced Obsessive-Compulsive Disorder in Mice by Inhibiting nNOS and Augmenting Cortico-Striatal Serotonin Levels

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Study Overview The research investigates the potential therapeutic effects of plumbagin on mice models suffering …

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Traumatic brain injury
Differences in narrative discourse ability in traumatic brain injury and a neurotypical comparison group: Influence of age, education, and sex

by myneuronews October 2, 2025

by myneuronews October 2, 2025

Study Overview This research explores the narrative discourse abilities of individuals with traumatic brain injury …

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Traumatic brain injury
Absence from work in the 12 months following mild traumatic brain injury in Europe: a CENTER-TBI cohort study

by myneuronews October 1, 2025

by myneuronews October 1, 2025

Study Overview This research delves into the patterns of absence from work experienced by individuals …

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Traumatic brain injury
Impact of > 24 h sustained wakefulness and subsequent recovery sleep on time-dependent changes in microRNA factors of individuals with post-acute phase mild traumatic brain injury

by myneuronews October 1, 2025

by myneuronews October 1, 2025

Study Overview The research investigates the effects of prolonged wakefulness exceeding 24 hours on individuals …

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Traumatic brain injury
Influence of traumatic brain injury on serum levels of pituitary, thyroid, adrenal and gonadal hormones

by myneuronews October 1, 2025

by myneuronews October 1, 2025

Impact of Traumatic Brain Injury on Hormonal Levels Traumatic brain injury (TBI) can profoundly alter …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]