Tag:

TBI

Traumatic brain injury
Perampanel for alleviation of secondary injury in traumatic brain injury (PEACE-TBI): a protocol for a phase-II multicentre randomised clinical trial

by myneuronews August 19, 2025

by myneuronews August 19, 2025

Study Overview The clinical trial, known as PEACE-TBI, is designed to evaluate the effectiveness of …

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Traumatic brain injury
A Randomized Sham-Controlled Trial of Heart Rate Variability Biofeedback Following Traumatic Brain Injury (TBI)

by myneuronews August 19, 2025

by myneuronews August 19, 2025

Study Overview The trial aimed to assess the effectiveness of heart rate variability biofeedback as …

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Traumatic brain injury
Low Utility and Yield of Routine Outpatient CT Imaging in Patients With Mild Traumatic Brain Injury and Intracranial Hemorrhage

by myneuronews August 18, 2025

by myneuronews August 18, 2025

Study Overview The research critically examines the utility of routine outpatient computed tomography (CT) imaging …

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Traumatic brain injury
Impact of oxygen and carbon dioxide levels on mortality in moderate to severe traumatic brain injury: a systematic review and meta-analysis

by myneuronews August 15, 2025

by myneuronews August 15, 2025

Study Overview This systematic review and meta-analysis focus on the correlation between oxygen and carbon …

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Traumatic brain injury
Glasgow Coma Scale Score at Admission in Traumatic Brain Injury Patients: A Multicenter Observational Analysis

by myneuronews August 14, 2025

by myneuronews August 14, 2025

Study Overview This multicenter observational analysis focuses on the role of the Glasgow Coma Scale …

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Traumatic brain injury
Glasgow Coma Scale Score at Admission in Traumatic Brain Injury Patients: A Multicenter Observational Analysis

by myneuronews August 14, 2025

by myneuronews August 14, 2025

Study Overview The purpose of this research was to assess the Glasgow Coma Scale (GCS) …

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Traumatic brain injury
Context Matters: Influence of Injury Context on Long-Term Psychiatric and Cognitive Outcomes in Combat Veterans With Mild Traumatic Brain Injury History

by myneuronews August 13, 2025

by myneuronews August 13, 2025

Injury Context and Its Relevance The circumstances surrounding a mild traumatic brain injury (mTBI) can …

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Traumatic brain injury
Exercise-Induced Symptom Exacerbation and Adverse Events in Moderate-to-Severe Traumatic Brain Injury

by myneuronews August 13, 2025

by myneuronews August 13, 2025

Exercise Effects on Symptoms Engaging in exercise after a traumatic brain injury (TBI) has shown …

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Traumatic brain injury
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury

by myneuronews August 12, 2025

by myneuronews August 12, 2025

Study Overview This research investigates the connection between gut-derived neurotoxin trimethylamine N-oxide (TMAO) and the …

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Traumatic brain injury
Cognitive Proficiency after Traumatic Brain Injury in Children

by myneuronews August 11, 2025

by myneuronews August 11, 2025

Cognitive Assessment Techniques Cognitive assessment techniques are essential for evaluating the impact of traumatic brain …

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Association of serum inflammasome proteins and pediatric traumatic brain injury severity
BACKGROUND: Pediatric traumatic brain injury (pTBI) often leads to cognitive, behavioral, and motor impairments. NLRP3 inflammasome proteins, such as ASC and caspase-1, may serve as biomarkers for TBI severity due to their role in neuroinflammation. This study aims to assess the association between serum ASC and caspase-1 levels and TBI severity in pediatric patients.
Linking a Deep Learning Model for Concussion Classification with Reorganization of Large-Scale Brain Networks in Female Youth
Concussion, or mild traumatic brain injury, is a significant public health challenge, with females experiencing high rates and prolonged symptoms. Reliable and objective tools for early diagnosis are critically needed, particularly in pediatric populations, where subjective symptom reporting can be inconsistent and neurodevelopmental factors may influence presentation. Five minutes of resting-state (RS) EEG data were […]
Neuroprotective Effects of Low-Intensity Pulsed Ultrasound in Chronic Traumatic Encephalopathy Induced by Repetitive Head Collisions: A Narrative Review
The repeated head impacts experienced by athletes have attracted significant interest from both the public and the scientific community; however, the neurobiological effects following the games are not well understood. For example, a single football match carries the risk of repeated concussive and subconcussive head impacts, which can increase the risk of developing neurodegenerative diseases. […]
Comparative predictive validity of a psychological risk screening tool in adults after mild traumatic brain injury
CONCLUSIONS: The STarT-C showed comparable prognostic value for post-concussion symptom outcomes with a battery of psychological questionnaires. Further research should consider if stratified risk using STarT-C high, medium, and low sub-categories improves targeted treatment referral decision making by clinicians and mTBI outcomes.
Brain injury contributes to dopaminergic neurodegeneration, Lewy body pathology, and Parkinsonism preclinically with outcomes altered by T cell modulation
Traumatic brain injury (TBI) increases the risk of Parkinson's disease (PD) development later in life, but much remains unknown regarding the mechanisms driving this relationship. A single, mild brain injury triggers resident and peripheral neuroinflammatory pathways that are similarly activated in PD patients, which could possibly increase susceptibility to neurodegeneration. In this study, we used […]