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therapy

Functional neurological disorders
The role of immunotherapy in a refractory case of acute hemorrhagic leukoencephalitis in a pediatric patient

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Clinical Presentation and Diagnosis In evaluating a pediatric patient presenting with acute hemorrhagic leukoencephalitis (AHLE), …

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Functional neurological disorders
Unveiling diverse clinical symptom patterns and neural activity profiles in major depressive disorder subtypes

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Clinical Symptom Patterns in Major Depressive Disorder In the realm of mental health, Major Depressive …

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Traumatic brain injury
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Overview of Neurophysiological Mechanisms Understanding the neurophysiological mechanisms underlying concussion involves delving into the complex …

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Functional neurological disorders
Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Fluid Biomarker Applications in Demyelinating Disorders Fluid biomarkers play a crucial role in the diagnosis …

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Traumatic brain injury
Characteristics of pediatric patients with sports-related concussions: A single site retrospective review

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Patient Demographics In the examination of pediatric patients with sports-related concussions, understanding the demographics of …

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Traumatic brain injury
Examining neurocognitive profiles and single-limb landing mechanics following anterior cruciate ligament reconstruction

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Neurocognitive Profiles Individuals who have undergone anterior cruciate ligament (ACL) reconstruction often experience a myriad …

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Functional neurological disorders
DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Mechanisms of DG9 Action DG9 has emerged as a pivotal compound in the realm of …

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Functional neurological disorders
Altered functional connectivity strength between structurally and functionally affected brain regions in visual snow syndrome

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Altered Connectivity in Visual Snow Syndrome Visual snow syndrome (VSS) is a perplexing neurological condition …

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Movement Disorders
Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single-center open-label clinical phase I trial (NEON trial)

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Study Overview The study aimed to investigate the safety and tolerability of intravenous liposomal GM1 …

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Headaches
Efficacy and Safety of Sodium Oxybate in Adults With Idiopathic Hypersomnia: A Randomized Controlled Trial

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Efficacy of Sodium Oxybate Sodium oxybate, a central nervous system depressant, has shown promise in …

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Guillain-Barré Syndrome Induced by Mycoplasma Pneumoniae: A Non-classical Presentation
Study Overview This study investigates a unique case of Guillain-Barré Syndrome (GBS) that arose following…
The Role of Metabolic Testing in the Diagnostic Evaluation of Adult NORSE: A Retrospective, Single-Centre Study
Study Overview The study under discussion investigates the significance of metabolic testing in diagnosing non-acute…
Alcohol Intake and Cardiovascular Outcomes in Patients With Atrial Fibrillation: RE-LY AF Registry Analysis
Study Overview The analysis derived from the RE-LY AF registry explores the implications of alcohol…
Long-term outcomes in leucine-rich glioma inactivated-1 autoimmune encephalitis and associated biomarkers of inflammation and neuronal and glial injury
Long-term outcomes Long-term outcomes in patients with leucine-rich glioma inactivated-1 (LGI1) autoimmune encephalitis are a…
Understanding personal preferences to promote exercise adherence in Parkinson’s disease
Understanding Preferences for Exercise Exploring individuals’ exercise preferences is essential in tailoring interventions that resonate…

Comparing the sensitivity and specificity of novel motor assessments for traumatic brain injury
CONCLUSION: MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.
Time-limited association between plasma transfusion and mortality in pediatric traumatic brain injury
CONCLUSION: This study reports a significant association between early plasma administration and a lower risk of 4-hour mortality among children with severe TBI that does not persist at or beyond 24 hours. While these data suggest that plasma resuscitation may extend the window for lifesaving intervention, additional prospective data are needed.
Chronic Traumatic Encephalopathy Neuropathologic Change Is Not Associated With Suicide in Former Athletes
There are important knowledge gaps and misunderstandings relating to chronic traumatic encephalopathy (CTE). A systematic review and meta-analysis, published in April of 2025, was designed to examine the prevalence, risk factors, and potential outcomes of CTE neuropathologic change (CTE-NC) in former athletes and concluded that suicide was a potential outcome of CTE-NC (Qi et al., […]
Cellular mechanisms of traumatic brain injury
Mild traumatic brain injury (mTBI) is an acute injury with immediate and medium-term symptom presentation. However, our mechanistic understanding of mTBI and how mechanical loading of soft cellular tissues leads to injury is limited. The aim of this review is to introduce this interdisciplinary field to non-experts and provide an overview of our current understanding […]
Regional and Global Changes in Brain Structure 1-Year Post Pediatric "Mild" Traumatic Brain Injury
OBJECTIVE: Despite the high prevalence of pediatric "mild" traumatic brain injury (pmTBI), very little is known about the long-term effects of injury on brain structure and how injuries manifest in the context of dynamic and regionally specific neurodevelopmental changes.