Tag:

therapy

Traumatic brain injury
Comment on Mavroudis et al. Post-Traumatic Epilepsy After Mild and Moderate Traumatic Brain Injury: A Narrative Review and Development of a Clinical Decision Tool. Reports 2025, 8, 193

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview The article by Mavroudis et al. presents a comprehensive evaluation of post-traumatic epilepsy …

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Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This study centers on the intricate relationships between cellular profiles in the human …

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Traumatic brain injury
A Clinical Practice Guideline for Adults With Concussion/Mild TBI: We Can’t Wait Until 2042

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Background and Rationale To understand the importance of addressing concussion and mild traumatic brain injury …

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Traumatic brain injury
Transitions in Independent Living, Productivity, and Social Relationships Among Individuals Sustaining Traumatic Brain Injury in Adolescence: A TBI Model Systems Investigation

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Study Overview The investigation focused on the trajectories of independent living, productivity, and social interactions …

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Headaches
Efficacy and safety of mirikizumab in paediatric participants with moderately-to-severely active ulcerative colitis (SHINE-1): a multicentre, open-label, non-randomised phase 2 trial

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Study Overview The study aimed to evaluate the effectiveness and safety of mirikizumab, a monoclonal …

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Traumatic brain injury
MSC-Exosomes alleviate cognitive impairment after mild traumatic brain injury by inhibiting ferroptosis via PI3K/AKT/mTOR-mediated upregulation of GPX4

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The research investigates the potential therapeutic effects of mesenchymal stem cell-derived exosomes (MSC-Exosomes) …

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Traumatic brain injury
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The investigation into the effects of targeted complement inhibition on outcomes following repetitive …

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Traumatic brain injury
Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Clinical Outcomes in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant challenge in …

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Headaches
Carotid and Vertebral Artery Dissections

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Epidemiology and Risk Factors Carotid and vertebral artery dissections are relatively uncommon vascular injuries characterized …

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Traumatic brain injury
2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila

by myneuronews November 18, 2025

by myneuronews November 18, 2025

Study Overview The investigation centers around understanding how innate immune signaling influences the outcomes of …

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The Use of Digital Neurocognitive Assessments to Assess Traumatic Brain Injury and Dementia in Older Trauma Patients: An Emergency Department Feasibility Study
Background/Objectives: Older adults are disproportionately affected by traumatic brain injuries (TBIs), representing a significant portion of TBI-related hospitalizations and deaths. The objective of this study was to evaluate the feasibility and effectiveness of BrainCheck (Braincheck, Inc., Austin, TX, USA), a digital cognitive assessment tool, in detecting acute TBI-related cognitive deficits in the context of dementia-related […]
Head injuries in intimate partner violence: cognitive, motor, and psychiatric symptoms
CONCLUSION: IPV groups reported more health issues than controls, and those with IPV-HI had the greatest rates of general health, cognitive, psychiatric, and neurobehavioral difficulties. These findings provide novel insight into IPV and IPV-related head injury outcomes.
Predictors of two consecutive knockout losses in ultimate fighting championship athletes
CONCLUSIONS: Among UFC athletes during this 8-year period, 23% sustained two knockout losses in a row. Predictors of two consecutive knockouts were older age, male sex, heavier weight class, and prior KO history, with prior KO history the only independent predictor. Recognizing prior knockout exposure as a key risk factor may help coaches and sports […]
The exercise and concussion health study (TECHS): Pilot and feasibility protocol
Mild traumatic brain injury (mTBI) is a prevalent neurological condition, affecting millions worldwide, and frequently resulting in persistent cognitive impairment that significantly impacts daily functioning. Current clinical management and recommendations lack evidence based therapeutic interventions, with treatment approaches limited to symptom monitoring and activity modification. Non-pharmaceutical interventions are needed to promote cognitive recovery and mitigate […]
Investigating associations between serum inflammatory cytokines at the time of second mild traumatic brain injury with acute neurological signs, axonal injury and behavioural outcomes in male Sprague-Dawley rats
Mild traumatic brain injury is a risk factor to sustaining future mild traumatic brain injuries and increased symptom severity and duration following a second mild traumatic brain injury. Inflammation during neurobiological recovery is hypothesized to influence susceptibility to poorer outcomes after repetitive mild traumatic brain injury. Here, we investigated whether the inflammatory response during neurobiological […]