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therapy

Functional neurological disorders
Computational Study of Pathogenic Variants in Phenylalanine-4-hydroxylase (PAH): Insights into Structure, Dynamics, and BH4 Binding

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Structural Insights into PAH Variants The study presents an intricate analysis of pathogenic variants in …

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Traumatic brain injury
Balance Impairments in Adolescents Post-Sports Concussion during Single and Dual Tasks

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Study Overview The investigation into balance impairments among adolescents recovering from sports-related concussions aims to …

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Functional neurological disorders
Rhynchophylline Reverses Obesity in High-Fat Diet-Induced Obese Rats by Regulating the Inflammatory Cascade and Blocking 3‑hydroxy-3-methylglutaryl Coenzyme A Reductase

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Effects of Rhynchophylline on Obesity In recent studies examining the effects of rhynchophylline on obesity, …

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Traumatic brain injury
Get Your Brain in the Game: Using Machine Learning to Predict Recovery Timelines Following Sports-Related Concussion

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Study Overview The research conducted aimed to investigate how machine learning can be utilized to …

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Functional neurological disorders
Longitudinal 12-Month Follow-Up of a Male Infant with CYP21A2 Compound Heterozygous Genotype in China: A Case Report

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Case Presentation The case centers on a male infant residing in China, who presented with …

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Headaches
Anti-nociceptive action of leonurine through TRPA1 and TRPV4 channels modulation

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Anti-nociceptive Mechanisms Leonurine, a bioactive compound derived from the plant Leonurus japonicus, exhibits significant anti-nociceptive …

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Traumatic brain injury
Language impairment is associated with faster progression in progressive supranuclear palsy-Richardson syndrome

by myneuronews July 19, 2025

by myneuronews July 19, 2025

Study overview The research focused on the connection between language impairments and the rate of …

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Traumatic brain injury
Sex differences in temperature rhythm disruption after traumatic brain injury

by myneuronews July 19, 2025

by myneuronews July 19, 2025

Sex Differences in Temperature Regulation Research has revealed that there are notable differences in temperature …

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Traumatic brain injury
Language impairment is associated with faster progression in progressive supranuclear palsy-Richardson syndrome

by myneuronews July 19, 2025

by myneuronews July 19, 2025

Association Between Language Impairment and Disease Progression Research indicates a significant relationship between language impairment …

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Traumatic brain injury
Sex differences in temperature rhythm disruption after traumatic brain injury

by myneuronews July 19, 2025

by myneuronews July 19, 2025

Research Background The intricate relationship between brain function and body temperature regulation has long been …

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Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip
Traumatic brain injuries (TBIs) are a risk factor for Alzheimer's disease (AD), and share several important pathological features including the development of neurofibrillary tangles (NFT) of tau protein. While this association is well established, the underlying pathogenesis is poorly defined and current treatment options remain limited, necessitating novel methods and approaches. In response we developed […]
Burden of Intracranial Hypertension and Patterns of Brain Injury on MRI: Secondary Analysis of the 2014-2017 "Approaches and Decisions for Acute Pediatric TBI" Study
CONCLUSIONS: Elevated ICP was prevalent in the ADAPT cohort. Ischemia and contusion were associated with the burden of ICP. Further research is needed to determine temporal relationships between elevated ICP and ischemia.
Player-Level Tackle Training Interventions in Tackle-Collision Sports: A Systematic Scoping Review
CONCLUSION: This review shows that a range of studies have been undertaken focusing on player-level training interventions. The quality of studies were rated as 'good', and all studies showed improvements in outcome measures. Coaches and policy makers should ensure tackle technique is profiled alongside other player characteristics, and an evidence-based approach to improving player tackling […]
Influences on the mental health and well-being of retired professional athletes from high contact team sports: a mixed methods systematic review
CONCLUSION: Retired HCTS athletes experience high levels of psychological distress and adverse alcohol use, but depression, anxiety and sleep disturbance were similar to population norms. These results call for greater support measures for retired athletes.
Quantifying Longitudinal Microstructural Changes in Mild Traumatic Brain Injury Patients with Mean Apparent Propagator MRI
Mean apparent propagator MRI (MAP-MRI) quantifies subtle alterations in tissue microstructure noninvasively and provides a more nuanced and comprehensive assessment of tissue architectural and structural integrity compared with other diffusion MRI techniques. We investigate the sensitivity of MAP-MRI-derived quantitative imaging biomarkers to detect previously unseen microstructural damage in patients with mild traumatic brain injuries (mTBI), […]