Tag:

therapy

Headaches
Gepants in Primary Care: A Targeted Approach to Acute and Preventive Treatment of Migraine

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Gepants Mechanism of Action Gepants are a novel class of oral medications specifically designed to …

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Traumatic brain injury
Clinical experience implanting a miniature externally powered vagus nerve stimulator

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview This study investigates the clinical experience surrounding the implantation of a miniature externally …

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Traumatic brain injury
Association between concomitant traumatic brain injury and unfavorable 1-year outcomes in patients with traumatic spinal cord injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The research focuses on the critical intersection of traumatic brain injury (TBI) and …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Traumatic brain injury
Association between concomitant traumatic brain injury and unfavorable 1-year outcomes in patients with traumatic spinal cord injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation centered around the relationship between traumatic brain injury (TBI) and the …

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Traumatic brain injury
Investigating Persistent Sympathovagal Dysregulation Following a Complex Dual Task in Concussed Athletes

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Study Overview This study investigates the phenomenon of sympathovagal dysregulation—a disruption in the balance between …

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Traumatic brain injury
Assessment of White Matter Changes Using Quantitative T1rho Mapping in an Open-Field Low-Intensity Blast Mouse Model of Mild Traumatic Brain Injury (mTBI)

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Study Overview The study investigates the impact of mild traumatic brain injury (mTBI) on white …

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Traumatic brain injury
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Neurobiological Mechanisms The mechanisms contributing to hyperexcitability in the dentate gyrus—a vital component of the …

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Traumatic brain injury
Bolt gun injury to central forehead, sagittal sinus and frontal lobes: A case report

by myneuronews June 24, 2025

by myneuronews June 24, 2025

Case Presentation A 32-year-old male was admitted to the emergency department following an accidental self-inflicted …

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Traumatic brain injury
Venous thromboembolism prophylaxis in adults with acute traumatic brain injury: a systematic review

by myneuronews June 24, 2025

by myneuronews June 24, 2025

Study Overview This systematic review focuses on the critical issue of venous thromboembolism (VTE) prophylaxis …

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Extracellular Vesicle-Derived microRNAs as Fluid Biomarkers in Neurodegenerative Diseases: A Systematic Review
Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. Extracellular vesicles (EVs) have emerged as promising biomarkers for neurodegeneration, owing to their accessibility in bodily fluids and dynamic molecular cargo, including microRNAs (miRNAs). The last decade has seen accumulating evidence for miRNA dysregulation in […]
P75NTR blockading inhibits Trem2+ M1 phenotype microglia activation and myelin damage following mild traumatic brain injury
The pathological basis underlying mild traumatic brain injury (mTBI)-induced long-term cognitive impairment is not fully understood. It is supposed that mTBI induces residential microglia activation rather than peripheral leukocyte infiltration to promote neuroinflammation, thus triggering myelin damage as well as cognitive impairment. The transformation of microglia towards a pro-inflammatory (M1 type) or anti-inflammatory (M2 type) […]
Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers
Mild traumatic brain injury can disrupt brain function and is associated with high morbidity and healthcare utilization. While many individuals recover from mild traumatic brain injury, a significant proportion experience long-term sequelae, collectively known as post-concussion syndrome. Symptoms of post-concussion syndrome include headache, dizziness, insomnia, cognitive processing difficulties and mental health disturbances. The disease burden […]
Comparison of Six Data Cleaning Methods for Determining Repetitive Head Impact Exposure in Youth Tackle Football
CONCLUSIONS: These findings highlight the impact of data cleaning on HAE quantification in youth tackle football. Although video verification remains best practice, it is resource intensive. Time-windowed, algorithm-classified data may serve as an efficient proxy in similar cohorts, though researchers should recognize its limitations. Findings support the need for standardized data cleaning methods and transparent […]
Differences in symptom duration and return to sport following sport-related concussion between French-speaking Canadian and European athletes
CONCLUSION: SRC recovery times differ significantly by geography and sex in French-speaking athletes. European athletes and males report shorter symptom and RTS durations.