The Connections Between Pain and Itch: Shared Neuroimmune Mechanisms and Therapeutic Implications
Shared Neuroimmune Mechanisms The interplay between the nervous system and the immune system plays a crucial role in understanding the […]
Remnant cholesterol level modified the effects of intensive systolic blood pressure lowering treatment in high-risk hypertensive patients: a post hoc analysis of the ESPRIT trial
Study Overview The research presented in the context of the ESPRIT trial focuses on how levels of remnant cholesterol may
Guillain-Barré Syndrome as the Initial Manifestation of Lyme Disease: Diagnostic Challenges
Understanding Guillain-Barré Syndrome Guillain-Barré Syndrome (GBS) is a rare neurological disorder characterized by the body’s immune system mistakenly attacking peripheral
miR-217-5p Regulates Microglia-Related Neuroinflammation via NF1 and Further Modulates Chronic Constriction Injury-Induced Neuropathic Pain
Study Overview This study investigates the role of miR-217-5p in the regulation of microglia-related neuroinflammation and its subsequent effects on
Prevalence of Neck Pain and Disability in Patients With Concussion: A Survey Study
Study Overview The investigation explored the occurrence of neck pain and associated disabilities among individuals who have experienced concussions. Concussions
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Treatment-seeking and perceived helpfulness among individuals with persistent post-concussion symptoms
Treatment-seeking Behavior Individuals who experience persistent post-concussion symptoms (PPCS) often exhibit varied patterns in their treatment-seeking behavior. After sustaining a
The neural transdifferentiation potential of bone marrow mesenchymal stem cells
Neural Transdifferentiation Mechanisms The process of neural transdifferentiation in bone marrow mesenchymal stem cells (BM-MSCs) involves a series of intricate
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Optic chiasmal neuritis: clinical features, aetiologies, MRI patterns and prognosis in a real-world cohort
Clinical Features and Presentation Optic chiasmal neuritis is characterized by a variety of clinical features that can significantly impact a
Failure of early B cell tolerance and possible BCR signaling dysregulation underlie NF155-mediated autoimmune nodopathies
Mechanisms of B Cell Tolerance Failure B cell tolerance is a critical mechanism that prevents the activation of autoreactive B
Case report: Unilateral optic atrophy and intracranial hypertension in anti-NF155 nodopathy: a case managed with sequential efgartigimod and rituximab
Clinical Presentation The case in question involved a patient diagnosed with unilateral optic atrophy and intracranial hypertension, specifically linked to