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traumatic brain injury

Traumatic brain injury
A sensor-based gait measure for identifying invalid performance in simulated mTBI: an experimental proof of concept

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Study Overview This study explores the development and evaluation of a sensor-based system designed to …

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Traumatic brain injury
The clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury (STOP-D): study protocol for a multi-centre randomised controlled trial

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Study Overview This rigorous research project focuses on the potential effectiveness of sertraline, an antidepressant …

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Traumatic brain injury
The clinical significance of serum LY86-AS1 in the early detection and prognostic evaluation of traumatic brain injury

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Serum LY86-AS1 and Traumatic Brain Injury Recent research indicates that LY86-AS1, a long non-coding RNA, …

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Traumatic brain injury
Concussions in Portuguese Professional Football: A Preliminary Epidemiological Study

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Background of Concussions Concussions are a common form of traumatic brain injury (TBI) that occur …

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Traumatic brain injury
Timing of definitive fracture fixation in patients with concomitant traumatic brain injuries – A systematic review of the literature by the IMPACT group

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Study Overview This systematic review focuses on the timing of definitive fracture fixation in patients …

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Traumatic brain injury
Impact of Modified Brain Injury Guideline Incorporating Neurosurgical Consultation on Resource Utilization and Follow-Up Care in Complicated Mild Traumatic Brain Injury

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Study Overview This investigation centers on the outcomes associated with the implementation of an updated …

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Traumatic brain injury
The Relationship of Prior Concussion and Contact Sport Exposure With Cortical Macro and Microstructure

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Study Overview The investigation focused on the potential effects of previous concussions and engagement in …

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Traumatic brain injury
Telerehabilitation for mild traumatic brain injury patients: patients’ preferences in Aotearoa New Zealand

by myneuronews October 27, 2025

by myneuronews October 27, 2025

Patient Preferences Understanding patient preferences in the context of telerehabilitation for mild traumatic brain injury …

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Traumatic brain injury
Factor analysis of neuropsychological attention measures with mild traumatic brain injury patients

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Study Overview This research investigates how various neuropsychological measures of attention are affected in patients …

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Traumatic brain injury
AQP4 in cerebrospinal fluid correlates with severity and prognosis in moderate to severe traumatic brain injury

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Background and Rationale Traumatic brain injury (TBI) is a significant public health concern, often resulting …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
The relationship between dispositional mindfulness and psychological, cognitive, and functional outcomes following mild traumatic brain injury
Background: Most individuals who sustain a mild uncomplicated Traumatic Brain Injury (mTBI) recover within 1-3 months. However, a significant proportion consistently report ongoing cognitive, psychological, and somatic sequelae, which can be functionally disabling and hinder active participation in society following injury. The present study examined dispositional mindfulness as a targetable protective factor as it pertains […]
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Multimodal Canonical Correlation Analysis with Joint Independent Component Analysis (mCCA+jICA) of IVIM and ASL MRI Reveals Perfusion and Diffusion Abnormalities in mTBI-A Pilot Study
Mild traumatic brain injury (mTBI) frequently causes subtle brain changes that are difficult to detect with conventional diagnostic approaches. In this exploratory pilot study, we combined tri-exponential intravoxel incoherent motion (IVIM) and pseudocontinuous arterial spin labeling (pCASL) MRI with Multimodal Canonical Correlation Analysis and joint independent component analysis (mCCA+jICA) to identify imaging signatures distinguishing mTBI […]