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traumatic brain injury

Traumatic brain injury
Efficacy and safety of exosomes from Wharton’s Jelly-derived mesenchymal stem cells in traumatic brain injury

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This investigation focuses on the therapeutic potential of exosomes derived from Wharton’s Jelly …

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Traumatic brain injury
Incidence rates of paediatric traumatic brain injury in Denmark – the development over three decades: a nationwide, population-based registry study

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This research focuses on the epidemiology of traumatic brain injuries (TBI) among children …

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Traumatic brain injury
Efficacy and safety of L-oxiracetam on cognitive function in patients with traumatic brain injury: a multicentre, randomised, double-blind, phase 3 clinical trial

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview The recent multicentre, randomised, double-blind, phase 3 clinical trial investigated the efficacy and …

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Traumatic brain injury
Traumatic Brain Injury Across the Lifespan and in Conflict Zones

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Understanding Traumatic Brain Injury Traumatic Brain Injury (TBI) occurs when an external force causes damage …

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Traumatic brain injury
Efficacy and safety of exosomes from Wharton’s Jelly-derived mesenchymal stem cells in traumatic brain injury

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Efficacy of exosomes Exosomes derived from Wharton’s Jelly mesenchymal stem cells (WJ-MSCs) have shown significant …

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Traumatic brain injury
Patterns, severity, and outcomes of traumatic brain injury in a regional referral hospital in Kenya: a retrospective cohort study

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Patterns of Traumatic Brain Injury Traumatic brain injury (TBI) is a significant public health challenge, …

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Traumatic brain injury
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared with Orthopedic Injury

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This study investigates the changes in DNA methylation of the brain-derived neurotrophic factor …

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Traumatic brain injury
Plasma and Imaging Biomarker Changes Following Rotational and Contusional Models of Traumatic Brain Injury in Adolescent Pigs

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Study Overview This research investigates the biochemical and imaging alterations resulting from two distinct forms …

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Traumatic brain injury
Development of a Fall-Specific Impact Testing Method to Evaluate Safety Helmet Performance and Injury Risk

by myneuronews December 9, 2025

by myneuronews December 9, 2025

Testing Method Development The creation of a testing method for evaluating the performance of safety …

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Traumatic brain injury
Within-Person Score Distribution Measures as Performance Validity Indicators in Service Members and Veterans with and without History of Mild Traumatic Brain Injury

by myneuronews December 9, 2025

by myneuronews December 9, 2025

Performance Validity Indicators Performance validity indicators (PVIs) are essential tools used to assess the credibility …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Alzheimer's Imaging Consortium
CONCLUSION: In a community-based cohort of older adults, TBI was associated with reductions in MRI hippocampal, frontal gray matter, and total cerebral gray matter volumes in females, but not males. Sex may portend different risk for later life atrophy after TBI, particularly in brain regions commonly affected by Alzheimer's disease and related dementias. Future work […]
Developing Topics
BACKGROUND: Alzheimer's Disease (AD) and Traumatic Brain Injury (TBI) are significant causes of disability in the USA, with millions affected and high treatment costs. Research has identified disrupted connections between auditory and visual sensory pathways in both conditions, leading to impairments in balance, sleep, posture, motor function, sensory integration (including visual-vestibular), and emotional regulation. These […]