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treatment options

Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein) plays a pivotal role in the pathophysiology …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP The role of ALOX5AP (Arachidonate 5-Lipoxygenase Activating Protein) in the pathogenesis …

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Functional neurological disorders
Epileptic seizure biophysics: the role of local voltage difference

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Understanding Seizure Mechanisms Seizures are complex neurological events that arise from abnormal electrical activity in …

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Functional neurological disorders
Feasibility trial of a self-help digital intervention for functional cognitive disorder

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Study Objectives The primary aim of this study was to evaluate the feasibility and potential …

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Functional neurological disorders
Lance-Adams Syndrome: Current Understanding and Management

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Understanding Lance-Adams Syndrome Lance-Adams Syndrome is characterized by a specific set of neurological symptoms that …

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Functional neurological disorders
Feasibility trial of a self-help digital intervention for functional cognitive disorder

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Background and Rationale Functional Cognitive Disorder (FCD) is a condition characterized by cognitive dysfunction that …

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Functional neurological disorders
Analysis of biased allelic enhancer activity of schizophrenia-linked common variants

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Biased allelic enhancer activity in schizophrenia Recent findings have highlighted the complexity of genetic factors …

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Traumatic brain injury
Provider Differences in Costs, Utilization and Quality of Primary Care for Traumatic Brain Injury in the Military

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Provider Profiles and Characteristics The landscape of primary care for traumatic brain injury (TBI) in …

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Traumatic brain injury
A double-blind, placebo-controlled, randomized, multi-centre, phase III study of MLC901 (NeuroAiDTMII) for the treatment of cognitive impairment after mild traumatic brain injury

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Study Overview This study aimed to evaluate the efficacy and safety of MLC901 (NeuroAiDTMII) as …

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Functional neurological disorders
Insights into the Diagnosis, Treatment, and Management of Prion Diseases

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Understanding Prion Diseases Prion diseases, a unique category of neurodegenerative disorders, are caused by misfolded …

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Severe Headache in a Child With Rickettsial Infection: A Case Report
Case Presentation A previously healthy 10-year-old boy was brought to the pediatric emergency department due…
Polygenic risk score of Alzheimer’s disease is associated with cognitive trajectories and phenotypes of cerebral organoids
Study Overview This study investigates the relationship between polygenic risk scores (PRS) for Alzheimer’s disease…
How Neurologists Combine Clinical Signs and Subjective Factors to Diagnose Epileptic and Functional Seizures: Insights From Seizure Video Analysis
Diagnostic Approaches in Epilepsy and Seizures The diagnosis of epilepsy and seizures is a complex…
Active Rehabilitation Following Acute Mild Traumatic Brain Injury: A Systematic Review
Active Rehabilitation Approaches Active rehabilitation is a crucial component in the recovery process following an…
Connecting the Dots: The Role of Pediatric Concussion on Pubertal Hormones and Psychological Health
Pediatric Concussions: Overview and Impact Pediatric concussions are a significant public health concern, with increasing…

Biomechanical injury risk analysis of a child dummy under cricket ball impacts: A finite element study
Children, while playing cricket, may get exposed to impact-related injuries. Most available studies have been done on adult players. Pediatric biomechanics concerning cricket ball impacts have been unexamined, supported by assumptions and surrogate models. This research used a finite element model of a child dummy, a ball, and a steel chair. Four conditions based on […]
Contact Role and Tackle Characteristics Shape Head Acceleration Exposure in Male Community Rugby: A Cohort Study Utilising Instrumented Mouthguards
CONCLUSIONS: Tackles and rucks are primary sources of HAEs, with risk shaped by posture, tackle height and player role. Lower tackle heights reduce ball carrier load but increase tackler exposure, indicating a potential safety trade-off. Younger players, particularly U13s, were more susceptible to secondary impacts (e.g. head-to-ground), potentially because of limited task-specific experience and underdeveloped […]
Soccer Heading Exposure-Dependent Microstructural Injury at Depths of Sulci in Adult Amateur Players
BACKGROUND AND OBJECTIVES: Repetitive head impacts (RHIs) in sports are associated with adverse clinical and neuropathologic outcomes, but there is limited evidence from in vivo human imaging studies to inform risk assessment, exposure standards, and interventions. We tested the association of RHI with in vivo microstructural disruption at the depths of cerebral sulci, a region […]
Connecting the Dots: The Role of Pediatric Concussion on Pubertal Hormones and Psychological Health
PURPOSE: Psychological health issues resulting from emotional dysregulation such as anxiety and depression following pediatric concussion are a public health concern, but the underlying mechanisms remain unclear. Puberty opens a window of vulnerability for emotion dysregulation and a link between pediatric concussion and hormonal deficits has been reported. We investigated the association between pubertal hormones […]
Patterns of Post-Concussive Symptoms Following Mild Traumatic Brain Injury: Longitudinal Data in Children and Adults to Examine Sex Differences Across the Life Span
OBJECTIVE: To examine sex- and age-related differences in patterns of post-concussive symptoms (PCS), across cognitive, somatic, emotional, and behavioral domains, and their recovery within the first 6 months after mild traumatic brain injury (mTBI), and their relation to participation.