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treatment options

Functional neurological disorders
Analysis of biased allelic enhancer activity of schizophrenia-linked common variants

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Biased allelic enhancer activity in schizophrenia Recent findings have highlighted the complexity of genetic factors …

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Functional neurological disorders
Randomised feasibility study evaluating eye movement desensitisation and reprocessing therapy for functional neurological disorder (MODIFI)

by myneuronews July 8, 2025

by myneuronews July 8, 2025

Study Objectives The primary aim of this study was to evaluate the feasibility of implementing …

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Dementia
Early outpatient clinical experience with xanomeline and trospium chloride for schizophrenia: a case report

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Study Overview This article presents a detailed examination of the early outpatient clinical experiences involving …

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Headaches
The efficacy and safety of intrathecal pemetrexed for leptomeningeal metastasis from non-small cell lung cancer: a single-arm meta-analysis of Chinese patients

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This study focuses on evaluating the effectiveness and safety of intrathecal pemetrexed in …

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Functional neurological disorders
Clinical and functional outcomes in pediatric patients with Rett syndrome: a 15-year retrospective study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Clinical Characteristics of Rett Syndrome Rett syndrome is a neurodevelopmental disorder predominantly affecting females, characterized …

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Functional neurological disorders
Cortical macro- and microstructural changes in isolated rapid eye movement sleep behavior disorder

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical macrostructural alterations The study of cortical macrostructural alterations in individuals with isolated rapid eye …

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Functional neurological disorders
Biopsychosocial prognostic indicators in Functional Neurological Disorder: A systematic review

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Prognostic Indicators Overview The systematic review highlights various prognostic indicators that have emerged as significant …

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Functional neurological disorders
Unveiling cortical criticality changes along the prodromal to the overt continuum of alpha-synucleinopathy

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical Criticality in Alpha-Synucleinopathy Recent research into alpha-synucleinopathy—disorders associated with the abnormal accumulation of the …

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Functional neurological disorders
What does a migraine aura look like?-A systematic review

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Migraine Aura Characteristics Migraine aura is a fascinating phenomenon that can manifest in various ways, …

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Traumatic brain injury
Long-Term Health-Related Quality of Life and Perceptions of Recovery in Adults Who Received Clinical Profiles Informed Care for Concussion

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Long-Term Quality of Life Outcomes Long-term health-related quality of life (HRQoL) outcomes for adults who …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
The relationship between dispositional mindfulness and psychological, cognitive, and functional outcomes following mild traumatic brain injury
Background: Most individuals who sustain a mild uncomplicated Traumatic Brain Injury (mTBI) recover within 1-3 months. However, a significant proportion consistently report ongoing cognitive, psychological, and somatic sequelae, which can be functionally disabling and hinder active participation in society following injury. The present study examined dispositional mindfulness as a targetable protective factor as it pertains […]
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Multimodal Canonical Correlation Analysis with Joint Independent Component Analysis (mCCA+jICA) of IVIM and ASL MRI Reveals Perfusion and Diffusion Abnormalities in mTBI-A Pilot Study
Mild traumatic brain injury (mTBI) frequently causes subtle brain changes that are difficult to detect with conventional diagnostic approaches. In this exploratory pilot study, we combined tri-exponential intravoxel incoherent motion (IVIM) and pseudocontinuous arterial spin labeling (pCASL) MRI with Multimodal Canonical Correlation Analysis and joint independent component analysis (mCCA+jICA) to identify imaging signatures distinguishing mTBI […]