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treatment options

Functional neurological disorders
Association of Striatal Dopaminergic Depletion and Cerebral Perfusion With Cognition in Brain-First and Body-First Parkinson’s Disease

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Dopaminergic Depletion and Cognition Dopaminergic depletion in the striatum is a critical factor in understanding …

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Dementia
Knowledge and attitudes towards Alzheimer’s disease among adult residents in Jiulongpo, Chongqing, China: A cross-sectional survey

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview This research aimed to explore the awareness and perceptions regarding Alzheimer’s disease among …

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Traumatic brain injury
Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The ADEPT trial is designed to investigate the effectiveness of accelerated intermittent theta …

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Dementia
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to explore the role of non-coding RNAs in the development …

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Functional neurological disorders
Myeloproliferative syndrome as a cause of chorea

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Myeloproliferative Syndromes Overview Myeloproliferative syndromes (MPS) are hematologic disorders characterized by the excessive production of …

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Headaches
Gepants in Primary Care: A Targeted Approach to Acute and Preventive Treatment of Migraine

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Gepants Mechanism of Action Gepants are a novel class of oral medications specifically designed to …

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Traumatic brain injury
Clinical experience implanting a miniature externally powered vagus nerve stimulator

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview This study investigates the clinical experience surrounding the implantation of a miniature externally …

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Functional neurological disorders
Lesion distribution and network mapping in dyskinetic cerebral palsy

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Lesion Characteristics in Dyskinetic Cerebral Palsy Lesion characteristics in dyskinetic cerebral palsy (DCP) play a …

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Traumatic brain injury
Clinical experience implanting a miniature externally powered vagus nerve stimulator

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview This research focuses on the clinical application of a miniature, externally powered vagus …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenic Role of Inflammatory Proteins In recent studies, inflammatory proteins have emerged as key players …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
The relationship between dispositional mindfulness and psychological, cognitive, and functional outcomes following mild traumatic brain injury
Background: Most individuals who sustain a mild uncomplicated Traumatic Brain Injury (mTBI) recover within 1-3 months. However, a significant proportion consistently report ongoing cognitive, psychological, and somatic sequelae, which can be functionally disabling and hinder active participation in society following injury. The present study examined dispositional mindfulness as a targetable protective factor as it pertains […]
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Multimodal Canonical Correlation Analysis with Joint Independent Component Analysis (mCCA+jICA) of IVIM and ASL MRI Reveals Perfusion and Diffusion Abnormalities in mTBI-A Pilot Study
Mild traumatic brain injury (mTBI) frequently causes subtle brain changes that are difficult to detect with conventional diagnostic approaches. In this exploratory pilot study, we combined tri-exponential intravoxel incoherent motion (IVIM) and pseudocontinuous arterial spin labeling (pCASL) MRI with Multimodal Canonical Correlation Analysis and joint independent component analysis (mCCA+jICA) to identify imaging signatures distinguishing mTBI […]