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treatment strategies

Stroke
Lipidomic profiling of the cerebrospinal fluid in moyamoya angiopathy patients

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Lipidomic profiling in moyamoya angiopathy Lipidomic profiling involves the comprehensive analysis of lipids within biological …

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Traumatic brain injury
A new characterisation of acute traumatic brain injury: the NIH-NINDS TBI Classification and Nomenclature Initiative

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Definition and Classification of TBI Traumatic brain injury (TBI) is a complex and multifaceted condition …

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Traumatic brain injury
A new characterisation of acute traumatic brain injury: the NIH-NINDS TBI Classification and Nomenclature Initiative

by myneuronews May 23, 2025

by myneuronews May 23, 2025

New Classification Framework The classification framework developed by the NIH-NINDS TBI Classification and Nomenclature Initiative …

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Traumatic brain injury
Traumatic Venous Sinus Thrombosis: Patient and Practice Patterns at a Major Trauma Center

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Patient Characteristics The characteristics of patients diagnosed with traumatic venous sinus thrombosis reveal crucial insights …

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Traumatic brain injury
Mild Traumatic Brain Injury Impairs Fear Extinction and Network Excitability in the Infralimbic Cortex

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Study Overview The study aimed to investigate the effects of mild traumatic brain injury (mTBI) …

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Traumatic brain injury
Mild Traumatic Brain Injury Impairs Fear Extinction and Network Excitability in the Infralimbic Cortex

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Impact of Mild Traumatic Brain Injury Mild traumatic brain injury (mTBI) poses significant challenges not …

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Traumatic brain injury
Subjective cognitive functioning in adults hospitalized after traumatic brain injury: A four-year follow-up

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Cognitive Functioning Post-TBI Traumatic brain injury (TBI) can profoundly impact cognitive functioning in adults. The …

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Functional neurological disorders
Convergent mapping of a tremor treatment network

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Mapping the Tremor Treatment Network The recent exploration into the tremor treatment network provides a …

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Functional neurological disorders
Regulating aggregation of an intrinsically disordered chaperone-like casein

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Characterization of Intrinsically Disordered Chaperone-Like Casein The study of intrinsically disordered proteins (IDPs) has become …

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Functional neurological disorders
Convergent mapping of a tremor treatment network

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Treatment Network Overview The recent study on the treatment network for tremors offers a thorough …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.