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treatment strategies

Functional neurological disorders
Neurological Emergencies in Incarcerated Patients: Clinical Characteristics, Severity, and Outcomes in an Emergency Department with an Embedded Neuro-Emergency Expert Model

by myneuronews October 29, 2025

by myneuronews October 29, 2025

Clinical Characteristics of Neurological Emergencies Neurological emergencies encompass a spectrum of acute conditions affecting the …

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Traumatic brain injury
The clinical significance of serum LY86-AS1 in the early detection and prognostic evaluation of traumatic brain injury

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Serum LY86-AS1 and Traumatic Brain Injury Recent research indicates that LY86-AS1, a long non-coding RNA, …

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Headaches
CD39(+) CD4(+) T Cells Influence Cluster Headache Risk via ADP/N-Acetylneuraminate and Choline Metabolic Pathways: Evidence from Mendelian Randomization

by myneuronews October 26, 2025

by myneuronews October 26, 2025

Study Overview This research investigates the influence of CD39(+) CD4(+) T cells on the risk …

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Dementia
Cerebral amyloid angiopathy-related inflammation superimposed on alpha-synucleinopathies: a case report and literature review

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Study Overview This case report examines the complex relationship between cerebral amyloid angiopathy (CAA) and …

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Traumatic brain injury
Factor analysis of neuropsychological attention measures with mild traumatic brain injury patients

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Study Overview This research investigates how various neuropsychological measures of attention are affected in patients …

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Functional neurological disorders
Possible bimodality in the age distribution of pediatric functional neurological disorder

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Pediatric Functional Neurological Disorder Overview Pediatric functional neurological disorder (FND) encompasses a range of neurologic …

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Functional neurological disorders
Possible bimodality in the age distribution of pediatric functional neurological disorder

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Assessment of Age Distribution The investigation into the age distribution of pediatric functional neurological disorder …

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Traumatic brain injury
AQP4 in cerebrospinal fluid correlates with severity and prognosis in moderate to severe traumatic brain injury

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Background and Rationale Traumatic brain injury (TBI) is a significant public health concern, often resulting …

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Functional neurological disorders
Possible bimodality in the age distribution of pediatric functional neurological disorder

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Characterizing Age Distribution Patterns The investigation into pediatric functional neurological disorder (FND) reveals intriguing patterns …

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Traumatic brain injury
Preliminary validation of a 10-item version of the Depression, Anxiety and Stress Scale in a mild traumatic brain injury sample

by myneuronews October 24, 2025

by myneuronews October 24, 2025

Assessment of Depression, Anxiety and Stress The assessment of psychological factors, specifically depression, anxiety, and …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]