Tag:

treatment strategies

Functional neurological disorders
Treatment of functional neurological disorder: an umbrella review of systematic reviews and meta-analyses

by myneuronews October 19, 2025

by myneuronews October 19, 2025

Treatment Approaches for FND Functional Neurological Disorder (FND) presents unique challenges for both patients and …

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Functional neurological disorders
Treatment of functional neurological disorder: an umbrella review of systematic reviews and meta-analyses

by myneuronews October 19, 2025

by myneuronews October 19, 2025

Treatment Approaches for FND Treatment approaches for Functional Neurological Disorder (FND) are becoming increasingly sophisticated, …

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Functional neurological disorders
Visualizing diagnostic delays in functional/dissociative seizures using the referral odyssey plot: A retrospective cohort study

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Visualizing Diagnostic Delays Diagnostic delays are a significant challenge in managing functional or dissociative seizures, …

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Functional neurological disorders
Visualizing diagnostic delays in functional/dissociative seizures using the referral odyssey plot: A retrospective cohort study

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Understanding Diagnostic Delays Diagnostic delays in functional neurological disorders (FND) present significant challenges for both …

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Functional neurological disorders
Visualizing diagnostic delays in functional/dissociative seizures using the referral odyssey plot: A retrospective cohort study

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Study Background Functional Neurological Disorder (FND) presents a unique challenge in clinical settings due to …

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Traumatic brain injury
Functional Connectivity Changes in Traumatic Brain Injury: A Systematic Review and Coordinate-Based Meta-Analysis of fMRI Studies

by myneuronews October 17, 2025

by myneuronews October 17, 2025

Study Overview The research focuses on the alterations in functional connectivity resulting from traumatic brain …

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Traumatic brain injury
Factors Associated With Persistent Symptoms Following Mild Traumatic Brain Injury

by myneuronews October 17, 2025

by myneuronews October 17, 2025

Study Overview The investigation into the factors linked to persistent symptoms following a mild traumatic …

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Traumatic brain injury
Understanding concussion in myalgic encephalomyelitis/chronic fatigue syndrome: Findings from the 2023 National Health Interview study

by myneuronews October 17, 2025

by myneuronews October 17, 2025

Concussion and Myalgic Encephalomyelitis Concussion is a type of traumatic brain injury that can have …

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Traumatic brain injury
The protocol for a randomized, sham-controlled trial of transcutaneous auricular neurostimulation for chronic pain and opioid withdrawal symptoms during a 4-day opioid taper for adults in the United States

by myneuronews October 17, 2025

by myneuronews October 17, 2025

Study Overview The research focuses on the effectiveness of transcutaneous auricular neurostimulation (tANS) as a …

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Functional neurological disorders
Prevalence and impact of comorbid PTSD, c-PTSD and EUPD on symptom severity in functional neurological disorder: protocol for a systematic review and meta-analysis

by myneuronews October 16, 2025

by myneuronews October 16, 2025

Prevalence of Comorbid Conditions Comorbid conditions such as post-traumatic stress disorder (PTSD), complex PTSD (c-PTSD), …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]