Tag:

treatment strategies

Traumatic brain injury
Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The ADEPT trial is designed to investigate the effectiveness of accelerated intermittent theta …

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Traumatic brain injury
Health care utilization and cost in the dual diagnosis of combined traumatic spinal cord injury and traumatic brain injury compared to traumatic brain injury alone: An analysis using MarketScan

by myneuronews June 28, 2025

by myneuronews June 28, 2025

Study Overview The research investigates the healthcare utilization and associated costs among patients diagnosed with …

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Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Phenotypes In chronic traumatic brain injury (TBI), individuals often manifest a variety of clinical …

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Headaches
Gepants in Primary Care: A Targeted Approach to Acute and Preventive Treatment of Migraine

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Gepants Mechanism of Action Gepants are a novel class of oral medications specifically designed to …

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Traumatic brain injury
Clinical experience implanting a miniature externally powered vagus nerve stimulator

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview This study investigates the clinical experience surrounding the implantation of a miniature externally …

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Traumatic brain injury
Association between concomitant traumatic brain injury and unfavorable 1-year outcomes in patients with traumatic spinal cord injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The research focuses on the critical intersection of traumatic brain injury (TBI) and …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Traumatic brain injury
Association between concomitant traumatic brain injury and unfavorable 1-year outcomes in patients with traumatic spinal cord injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation centered around the relationship between traumatic brain injury (TBI) and the …

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Traumatic brain injury
A Customized Neural Transcranial Magnetic Stimulation Target for Functional Disability Among Veterans With Co-Occurring Alcohol Use Disorder and Mild Traumatic Brain Injury: Protocol for a Pilot Randomized Controlled Trial

by myneuronews June 23, 2025

by myneuronews June 23, 2025

Study Overview The upcoming pilot randomized controlled trial aims to evaluate the effectiveness of a …

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Dementia
Stem Cell-Derived, Fully Differentiated Islets for Type 1 Diabetes

by myneuronews June 22, 2025

by myneuronews June 22, 2025

Background and Rationale The advancement of regenerative medicine has brought to the forefront the potential …

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The Use of Digital Neurocognitive Assessments to Assess Traumatic Brain Injury and Dementia in Older Trauma Patients: An Emergency Department Feasibility Study
Background/Objectives: Older adults are disproportionately affected by traumatic brain injuries (TBIs), representing a significant portion of TBI-related hospitalizations and deaths. The objective of this study was to evaluate the feasibility and effectiveness of BrainCheck (Braincheck, Inc., Austin, TX, USA), a digital cognitive assessment tool, in detecting acute TBI-related cognitive deficits in the context of dementia-related […]
Head injuries in intimate partner violence: cognitive, motor, and psychiatric symptoms
CONCLUSION: IPV groups reported more health issues than controls, and those with IPV-HI had the greatest rates of general health, cognitive, psychiatric, and neurobehavioral difficulties. These findings provide novel insight into IPV and IPV-related head injury outcomes.
Predictors of two consecutive knockout losses in ultimate fighting championship athletes
CONCLUSIONS: Among UFC athletes during this 8-year period, 23% sustained two knockout losses in a row. Predictors of two consecutive knockouts were older age, male sex, heavier weight class, and prior KO history, with prior KO history the only independent predictor. Recognizing prior knockout exposure as a key risk factor may help coaches and sports […]
The exercise and concussion health study (TECHS): Pilot and feasibility protocol
Mild traumatic brain injury (mTBI) is a prevalent neurological condition, affecting millions worldwide, and frequently resulting in persistent cognitive impairment that significantly impacts daily functioning. Current clinical management and recommendations lack evidence based therapeutic interventions, with treatment approaches limited to symptom monitoring and activity modification. Non-pharmaceutical interventions are needed to promote cognitive recovery and mitigate […]
Investigating associations between serum inflammatory cytokines at the time of second mild traumatic brain injury with acute neurological signs, axonal injury and behavioural outcomes in male Sprague-Dawley rats
Mild traumatic brain injury is a risk factor to sustaining future mild traumatic brain injuries and increased symptom severity and duration following a second mild traumatic brain injury. Inflammation during neurobiological recovery is hypothesized to influence susceptibility to poorer outcomes after repetitive mild traumatic brain injury. Here, we investigated whether the inflammatory response during neurobiological […]