Tag:

treatment strategies

Headaches
Diagnosing migraine from genome-wide genotype data: a machine learning analysis

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Background on Migraine and Genomics Migraine is a prevalent and often debilitating neurological condition characterized …

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Traumatic brain injury
Is injury-related parental stress in the acute phase following early childhood concussion associated with symptoms and recovery?

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Association Between Parental Stress and Child Recovery Research has increasingly highlighted the significant role that …

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Headaches
Voltammetric determination of sumatriptan in the presence of naproxen using a modified screen printed electrode

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Study Overview In recent years, the increasing prevalence of migraine headaches has heightened interest in …

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Traumatic brain injury
Echoes of the Battlefield: Five-Year Longitudinal Cognitive Trajectories show Trend of Recovery for Deployment-related mild TBI in the LIMBIC-CENC Cohort

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Longitudinal Cognitive Trajectories The concept of longitudinal cognitive trajectories is critical in understanding how cognitive …

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Traumatic brain injury
Echoes of the Battlefield: Five-Year Longitudinal Cognitive Trajectories show Trend of Recovery for Deployment-related mild TBI in the LIMBIC-CENC Cohort

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Cognitive Recovery Patterns The journey of cognitive recovery following a mild traumatic brain injury (mTBI) …

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Traumatic brain injury
PACAP a mediator of inflammation following trauma exposure and mild traumatic brain injury: Differential effects in males and females

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background on PACAP and Inflammation Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that plays …

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Traumatic brain injury
Hybrid membrane-coated Cyclosporine A nanocrystals preventing secondary brain injury via alleviating neuroinflammatory and oxidative stress

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Therapeutic Approach The therapeutic strategy explored in this study focuses on utilizing hybrid membrane-coated nanocrystals …

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Traumatic brain injury
Clinical comparisons between post-traumatic headache and migraine: A cross-sectional study

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Study Overview This study examined the clinical characteristics of post-traumatic headaches (PTH) in comparison to …

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Headaches
Efficacy, safety, and tolerability of chenodeoxycholic acid (CDCA) in adult patients with cerebrotendinous xanthomatosis (RESTORE): a randomized withdrawal, double-blind, placebo-controlled, crossover phase 3 study

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Efficacy of Chenodeoxycholic Acid Chenodeoxycholic acid (CDCA) has emerged as a critical therapeutic option for …

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Traumatic brain injury
Single-Quantum Sodium MRI at 3T for the Separation of Mono- and Bi-T2 Sodium Signals

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Study Overview The study investigates an innovative approach to magnetic resonance imaging (MRI) aimed at …

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Head injuries in intimate partner violence: cognitive, motor, and psychiatric symptoms
CONCLUSION: IPV groups reported more health issues than controls, and those with IPV-HI had the greatest rates of general health, cognitive, psychiatric, and neurobehavioral difficulties. These findings provide novel insight into IPV and IPV-related head injury outcomes.
The exercise and concussion health study (TECHS): Pilot and feasibility protocol
Mild traumatic brain injury (mTBI) is a prevalent neurological condition, affecting millions worldwide, and frequently resulting in persistent cognitive impairment that significantly impacts daily functioning. Current clinical management and recommendations lack evidence based therapeutic interventions, with treatment approaches limited to symptom monitoring and activity modification. Non-pharmaceutical interventions are needed to promote cognitive recovery and mitigate […]
Predictors of two consecutive knockout losses in ultimate fighting championship athletes
CONCLUSIONS: Among UFC athletes during this 8-year period, 23% sustained two knockout losses in a row. Predictors of two consecutive knockouts were older age, male sex, heavier weight class, and prior KO history, with prior KO history the only independent predictor. Recognizing prior knockout exposure as a key risk factor may help coaches and sports […]
Investigating associations between serum inflammatory cytokines at the time of second mild traumatic brain injury with acute neurological signs, axonal injury and behavioural outcomes in male Sprague-Dawley rats
Mild traumatic brain injury is a risk factor to sustaining future mild traumatic brain injuries and increased symptom severity and duration following a second mild traumatic brain injury. Inflammation during neurobiological recovery is hypothesized to influence susceptibility to poorer outcomes after repetitive mild traumatic brain injury. Here, we investigated whether the inflammatory response during neurobiological […]
Quantifying Mechanical Strain-Induced Membrane Damage in Early Neuronal Cells Using an In Vitro Traumatic Brain Injury Model
This protocol describes a reproducible workflow for modeling in vitro impact-induced traumatic brain injury (TBI) using a mechanical stretch system applied to differentiated SH-SY5Y human neuroblastoma cells cultured on polydimethylsiloxane (PDMS) substrates. The protocol integrates three primary components: (1) fabrication and surface modification of deformable PDMS chambers to support cellular adhesion, (2) partial differentiation of […]